An Unknown Genetic Defect Increases Venous Thrombosis Risk, through Interaction with Protein C Deficiency Sandra J. Hasstedt, Edwin G. Bovill, Peter.

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Presentation transcript:

An Unknown Genetic Defect Increases Venous Thrombosis Risk, through Interaction with Protein C Deficiency Sandra J. Hasstedt, Edwin G. Bovill, Peter W. Callas, George L. Long The American Journal of Human Genetics Volume 63, Issue 2, Pages 569-576 (August 1998) DOI: 10.1086/301947 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 1 Distribution of protein C levels among carriers of the His107Pro protein C mutation, by thrombosis diagnosis. The American Journal of Human Genetics 1998 63, 569-576DOI: (10.1086/301947) Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 2 Distribution of protein C levels among male and female carriers and noncarriers of the His107Pro protein C mutation, by age at first thrombotic episode. The American Journal of Human Genetics 1998 63, 569-576DOI: (10.1086/301947) Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 3 Selected descendants of the parents of the proband (individual 3). Unaffected individuals whose current age is not given were not studied. The American Journal of Human Genetics 1998 63, 569-576DOI: (10.1086/301947) Copyright © 1998 The American Society of Human Genetics Terms and Conditions