Francisco Leyva et al. JACC 2017;70:

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Presentation transcript:

Francisco Leyva et al. JACC 2017;70:1216-1227 Cardiac Resynchronization Therapy in Nonischemic Cardiomyopathy With or Without Left Ventricular Midwall Fibrosis We sought to determine whether cardiac resynchronization therapy–defibrillation (CRT-D) was superior to cardiac resynchronization therapy–pacing (CRT-P) in patients with nonischemic cardiomyopathy (NICM) with or without midwall fibrosis. (A) Four-chamber and short-axis inversion recovery late gadolinium enhancement cardiac magnetic resonance images show midwall enhancement (yellow arrows) in the interventricular septum, typical of midwall fibrosis. (B) Survival curves for patients with NICM demonstrated that CRT-D was superior to CRT-P for total mortality and the presence of midwall fibrosis affected the likelihood of sudden cardiac death. Francisco Leyva et al. JACC 2017;70:1216-1227 2017 The Authors