Transmission of Action Potential Across a Synapse
axon terminal synaptic cleft Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. axon terminal synaptic vesicles enclose neuro- transmitters synaptic cleft
presynaptic membrane neurotransmitter postsynaptic membrane Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. presynaptic membrane neurotransmitter postsynaptic membrane
Fig. 17.5d neuro- transmitter receptor Na+ postsynaptic neuron Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. neuro- transmitter receptor Na+ postsynaptic neuron
axon terminal synaptic cleft Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. Ca2+ synaptic vesicles enclose neuro- transmitters synaptic cleft
2. Neuro- transmitters are released and bind to receptors on the Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Neuro- transmitters are released and bind to receptors on the postsynaptic membrane. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. presynaptic membrane neurotransmitter postsynaptic membrane Ca2+ synaptic vesicles enclose neuro- transmitters synaptic cleft
2. Neuro- transmitters are released and bind to receptors on the Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Neuro- transmitters are released and bind to receptors on the postsynaptic membrane. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. presynaptic membrane neurotransmitter postsynaptic membrane Ca2+ 3. When an excitatory neuro- transmitter binds to a receptor, Na+ diffuses into the postsynaptic neuron, and an action potential begins. synaptic vesicles enclose neuro- transmitters neuro- transmitter receptor Na+ postsynaptic neuron synaptic cleft
2. Neuro- transmitters are released and bind to receptors on the Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Neuro- transmitters are released and bind to receptors on the postsynaptic membrane. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. cell body of postsynaptic neuron presynaptic membrane neurotransmitter postsynaptic membrane Ca2+ 3. When an excitatory neuro- transmitter binds to a receptor, Na+ diffuses into the postsynaptic neuron, and an action potential begins. synaptic vesicles enclose neuro- transmitters neuro- transmitter receptor Na+ postsynaptic neuron synaptic cleft