Hypertensive nephrosclerosis in African Americans versus Caucasians

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Hypertensive nephrosclerosis in African Americans versus Caucasians Carmelita Marcantoni, Li-Jun Ma, Charles Federspiel, Agnes B. Fogo  Kidney International  Volume 62, Issue 1, Pages 172-180 (July 2002) DOI: 10.1046/j.1523-1755.2002.00420.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Lesions in hypertensive nephrosclerosis. Global glomerulosclerosis was categorized as either the solidified type (A), with solidification of the glomerular tuft, or the obsolescent type (B) with global sclerosis with retraction of the tuft and Bowman's space occupied by collagenous material. Vascular sclerosis was manifest by medial hypertrophy and intimal fibrosis (C). Segmental sclerosis (D) was present more frequently in association with solidified global glomerulosclerosis (A, B, D, Jones' silver stain, ×400; C, periodic Acid Schiff stain, ×400): Kidney International 2002 62, 172-180DOI: (10.1046/j.1523-1755.2002.00420.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 “Disappearing” glomeruli in hypertensive nephrosclerosis. Some globally sclerotic glomeruli show dissolution of Bowman's capsule, with a continuum of the sclerotic glomerulus and the fibrotic interstitium, which ultimately leads to disappearance of a recognizable glomerular tuft (A,B, Jones' silver stain, ×400). Kidney International 2002 62, 172-180DOI: (10.1046/j.1523-1755.2002.00420.x) Copyright © 2002 International Society of Nephrology Terms and Conditions