Gene expression profiling diagnosis through DNA molecular computation

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Presentation transcript:

Gene expression profiling diagnosis through DNA molecular computation Allen P. Mills, Jr. TRENDS in Biotechnology, vol 20 No.4 (2002) 137-140 MEC Seminar Su Dong Kim 2003. 1. 9. (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

(C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/ Introduction Gene expression profiling ; (mRNA : cDNA) DNA microarray Adleman DNA self-assembly computer DNA neural network Expression profiling should be feasible using a DNA neural network acting directly on cDNA (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

(C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/ DNA computation Adleman’s in vitro DNA solution of HPP (1994) (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

(C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/ Perceptron (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

(C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/ DNA Neural Networks (1) Steps in forming an axon (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

(C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/ DNA Neural Networks (2) Single layer DNA Neural Network represented by DNA (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

(C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/ Experimental Results (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

Expression Profiling Neural Network (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/

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