Cardiac support device, restrictive mitral valve annuloplasty, and optimized medical treatment: A multimodality approach to nonischemic cardiomyopathy

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Cardiac support device, restrictive mitral valve annuloplasty, and optimized medical treatment: A multimodality approach to nonischemic cardiomyopathy Jerry Braun, MD, Agnieszka Ciarka, MD, PhD, Michel I.M. Versteegh, MD, Victoria Delgado, MD, Eric Boersma, MD, PhD, Harriette F. Verwey, MD, PhD, Martin J. Schalij, MD, PhD, Jeroen J. Bax, MD, PhD, Robert A.E. Dion, MD, PhD, Nico R. van de Veire, MD, PhD, Robert J.M. Klautz, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 142, Issue 3, Pages e93-e100 (September 2011) DOI: 10.1016/j.jtcvs.2010.12.027 Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Survival estimated by Kaplan–Meier method for all patients. B, Survival estimated by Kaplan–Meier method for cohorts with and without a cardiac support device (CSD). Patients at risk per cohort are shown under the horizontal axis (CSD presented in boldface; no-CSD in regular type). HR, Hazard ratio; CI, confidence intervals. The Journal of Thoracic and Cardiovascular Surgery 2011 142, e93-e100DOI: (10.1016/j.jtcvs.2010.12.027) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Clinical status according to New York Heart Association (NYHA) criteria at baseline and at late follow-up. The Journal of Thoracic and Cardiovascular Surgery 2011 142, e93-e100DOI: (10.1016/j.jtcvs.2010.12.027) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Left panel: Evolution of left ventricular end-diastolic volumes (LVEDV) preoperatively, at early postoperative follow-up, and at long-term follow-up in patients with a cardiac support device (CSD+, solid line) and without a cardiac support device (CSD−, interrupted line). P value given for 2-way analysis of variance for repeated measurements, comparing between subjects effects with CSD as a factor. Significant value indicates a difference in development of volumes over time between both groups. Comparisons within groups for volumes at different times were performed with Bonferroni post-hoc comparisons and indicated as follows: *P < .01 versus preoperative, †P < .01 versus early postoperative echocardiogram. Right panel: Similarly, evolution of left ventricular end-systolic volumes (LVESV) throughout the follow-up. The Journal of Thoracic and Cardiovascular Surgery 2011 142, e93-e100DOI: (10.1016/j.jtcvs.2010.12.027) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions