Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled.

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Presentation transcript:

Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled trial Susanne Lau, MD, PhD, Kerstin Gerhold, MD, PhD, Kurt Zimmermann, PhD, Charlotte W. Ockeloen, MD, Siri Rossberg, MD, Petra Wagner, Claudia Sulser, MD, Rita Bunikowski, MD, Imke Witt, MD, Juliane Wauer, MD, John Beschorner, MD, Georg Menke, PhD, Eckard Hamelmann, MD, PhD, Ulrich Wahn, MD, PhD Journal of Allergy and Clinical Immunology Volume 129, Issue 4, Pages 1040-1047 (April 2012) DOI: 10.1016/j.jaci.2012.02.005 Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Study design. Journal of Allergy and Clinical Immunology 2012 129, 1040-1047DOI: (10.1016/j.jaci.2012.02.005) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Flow chart of study participants (light gray, intervention phase; green, follow-up phase). Journal of Allergy and Clinical Immunology 2012 129, 1040-1047DOI: (10.1016/j.jaci.2012.02.005) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Total study group with double and single parental heredity (n = 606): eczema-free survival rates in the active and placebo intervention groups up to 3 years of life (ITT evaluation). Journal of Allergy and Clinical Immunology 2012 129, 1040-1047DOI: (10.1016/j.jaci.2012.02.005) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Single parental heredity subgroup (either in the mother or the father, n = 296): eczema-free survival rates in the active and placebo intervention groups up to 3 years of life (ITT evaluation). Journal of Allergy and Clinical Immunology 2012 129, 1040-1047DOI: (10.1016/j.jaci.2012.02.005) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions