Pneumococcal Disease Prevention in Children: Issues in the Era of PCVs

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Presentation transcript:

Pneumococcal Disease Prevention in Children: Issues in the Era of PCVs

Effect of PCV Use on IPD in Children

Effect of PCV Use on IPD in Adults

Composition of PCVs

The Importance of Targeting Additional Serotypes With PCV13

Effect of PCV13 Use on Serotype Distribution in the United States

Effect of PCV10 Use on Serotype Distribution in Iceland

Herd Effect: PCV Use and Serotype Distribution in Adults

Herd Effect: PCV Use and Pneumonia in Adults

Herd Effect: PCV Use and Nasopharyngeal Carriage in Unvaccinated Children

Herd Effect: PCV Use and IPD

Herd Effect: Haemophilus Influenzae Vaccination

Reducing Nasopharyngeal Carriage: Effect of PCV10 Use Across All Age Groups

Reducing Nasopharyngeal Carriage: Effect on Serotype Prevalence

Serotype Replacement: PCV7 Use and Otitis Media

Serotype Replacement: High-Valent PCV Use and IPD in Germany

Serotype Replacement: Effect of PCV Use on Carriage Rates and IPD Incidence in Iceland

Invasiveness of Nonvaccine Serotypes

PCV Use and Antibiotic-Nonsusceptible Serotypes

PCV Use and Antibiotic Usage

Looking Ahead: Improving Effectiveness Against Virulent Pneumococci

PCV10 vs PCV13: Optimizing Clinical Use

Conclusions

Abbreviations