Figure 1 Antiplatelet and anticoagulant pathways

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Presentation transcript:

Figure 1 Antiplatelet and anticoagulant pathways Figure 1 | Antiplatelet and anticoagulant pathways. Antiplatelet and anticoagulant pathways are interrelated and each contributes to thrombosis. Antithrombotic drug combinations affect these pathways, decreasing the risk of ischaemic events, but also increasing the risk of bleeding. F, factor; GP, glycoprotein; PAR, protease-activated receptor; TF, tissue factor; TxA2, thromboxane A2. Bhatt, D. L. (2018) Advances in atherosclerosis, atrial fibrillation, and valvular disease Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.212