Bariatric Surgery Restores Gut-Brain Signaling to Reduce Fat Intake Stephanie Caligiuri, Paul J. Kenny Cell Metabolism Volume 25, Issue 2, Pages 221-222 (February 2017) DOI: 10.1016/j.cmet.2017.01.017 Copyright © 2017 Elsevier Inc. Terms and Conditions
Figure 1 Gastric Bypass in Rats Restores Gut-Brain Signaling Left panel: obese animals show desensitized intestinal production of the OEA, which serves as a satiety signal for dietary lipids, blunted striatal dopamine responses to high-fat food, and increased preference for high-fat food. Right panel: Roux-en-Y gastric bypass surgery in rats restores intestinal OEA production in response to dietary lipids, dramatically enhances striatal dopamine transmission in response to high-fat food, and reduces preference for high-fat food. Cell Metabolism 2017 25, 221-222DOI: (10.1016/j.cmet.2017.01.017) Copyright © 2017 Elsevier Inc. Terms and Conditions