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Hap1 and GABA: Thinking about food intake

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1 Hap1 and GABA: Thinking about food intake
Stephen C. Woods, Randy J. Seeley  Cell Metabolism  Volume 3, Issue 6, Pages (June 2006) DOI: /j.cmet Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Postulated model for the influence of Huntingtin-associated protein-1 on food intake in the hypothalamus GABA stimulates GABAA receptors, triggering events that lead to continued eating. Hap1 enhances this process, and Huntingtin-associated protein-1 (Hap1) levels are in turn increased by fasting and decreased by feeding and insulin. Cell Metabolism 2006 3, DOI: ( /j.cmet ) Copyright © 2006 Elsevier Inc. Terms and Conditions


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