P Bodies, Stress Granules, and Viral Life Cycles

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Presentation transcript:

P Bodies, Stress Granules, and Viral Life Cycles Carla J. Beckham, Roy Parker Cell Host & Microbe Volume 3, Issue 4, Pages 206-212 (April 2008) DOI: 10.1016/j.chom.2008.03.004 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 Cytoplasmic Cycling of mRNA mRNA in the cytoplasm of eukaryotic cells may either engage in translation or be sequestered into translationally repressed mRNPs. Stress granules in mammals are formed during various cellular stresses and include mRNA, translation initiation factors, and TIA-R proteins. Alternatively, mRNA can be sequestered into P bodies where the mRNA is stored for future use in translation or decapped and degraded. Cell Host & Microbe 2008 3, 206-212DOI: (10.1016/j.chom.2008.03.004) Copyright © 2008 Elsevier Inc. Terms and Conditions