In Stem Cell Transplantation by Limiting the Morbidity of Graft-versus-Host Disease Tolerance to Myeloablative Conditioning is Improved Nicolas Novitzky,

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Presentation transcript:

In Stem Cell Transplantation by Limiting the Morbidity of Graft-versus-Host Disease Tolerance to Myeloablative Conditioning is Improved Nicolas Novitzky, Valda Thomas, Cecile du Toit, Andrew Mcdonald Biology of Blood and Marrow Transplantation Volume 14, Issue 6, Pages 709-718 (June 2008) DOI: 10.1016/j.bbmt.2008.01.007 Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Overall survival of the patient population. Biology of Blood and Marrow Transplantation 2008 14, 709-718DOI: (10.1016/j.bbmt.2008.01.007) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Survival according to occurrence of GVHD. Biology of Blood and Marrow Transplantation 2008 14, 709-718DOI: (10.1016/j.bbmt.2008.01.007) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Survival according to diagnosis. The difference in the outcomes is not significant. CML indicates chronic myelogenous leukemia; NHL, non-hodgkin's lymphoma; MM, multiple myeloma; AL, acute leukemia. Biology of Blood and Marrow Transplantation 2008 14, 709-718DOI: (10.1016/j.bbmt.2008.01.007) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Treatment related mortality (TRM) and treatment failure due to disease recurrance is shown. It must be noted that 11 of these patients who relapsed (Rel) are alive in further remission following DLI. Biology of Blood and Marrow Transplantation 2008 14, 709-718DOI: (10.1016/j.bbmt.2008.01.007) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions