FMR1 gene CGG repeat variation within the normal range is not predictive of ovarian response in IVF cycles Scott J. Morin, Ashley W. Tiegs, Jason M.

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Presentation transcript:

FMR1 gene CGG repeat variation within the normal range is not predictive of ovarian response in IVF cycles Scott J. Morin, Ashley W. Tiegs, Jason M. Franasiak, Caroline R. Juneau, Kathleen H. Hong, Marie D. Werner, Yiping Zhan, Jessica Landis, Richard T. Scott Reproductive BioMedicine Online Volume 32, Issue 5, Pages 496-502 (May 2016) DOI: 10.1016/j.rbmo.2016.02.009 Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 The number of mature oocytes retrieved by extreme CGG repeat number in 3006 patients with second order polynomial modeling. No significant correlation was found between CGG repeat number and number of oocytes retrieved. Reproductive BioMedicine Online 2016 32, 496-502DOI: (10.1016/j.rbmo.2016.02.009) Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Receiver operating characteristic curve assessing the ability of normal range CGG repeat number to predict poor response (fewer than four oocytes retrieved) to ovarian stimulation in IVF. Area under the curve is 0.507, reflecting poor sensitivity and specificity for prediction of poor response. Reproductive BioMedicine Online 2016 32, 496-502DOI: (10.1016/j.rbmo.2016.02.009) Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions