Accelerated hemithoracic radiation followed by extrapleural pneumonectomy for malignant pleural mesothelioma Marc de Perrot, MD, MSc, Ronald Feld, MD,

Slides:

Advertisements

Similar presentations

Accelerated hemithoracic radiation followed by extrapleural pneumonectomy for malignant pleural mesothelioma Marc de Perrot, Ronald Feld, Natasha B Leighl,

Advertisements

Improved survival with pulmonary metastasectomy: An analysis of 1720 patients with pulmonary metastatic melanoma Rebecca P. Petersen, MD, MSc, Steven.

Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine, prophylactic radiotherapy, and systemic chemotherapy in patients with malignant.

Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine, prophylactic radiotherapy, and systemic chemotherapy in patients with malignant.

Marcelo Cypel, MD, MSc, Jonathan C

Max B. Mitchell, MD The Journal of Thoracic and Cardiovascular Surgery

Lost in translation The Journal of Thoracic and Cardiovascular Surgery

Synchronous multiple primary lung cancer: An increasing clinical occurrence requiring multidisciplinary management Delphine Trousse, MD, Fabrice Barlesi,

One in every 14 patients with early-stage lung cancer is not being treated! Benny Weksler, MD, MBA The Journal of Thoracic and Cardiovascular Surgery

Endoscopic ultrasound is inadequate to determine which T1/T2 esophageal tumors are candidates for endoluminal therapies Edward J. Bergeron, MD, Jules.

A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph.

Does the method of radiologic surveillance affect survival after resection of stage I non– small cell lung cancer? Traves D. Crabtree, MD, Varun Puri,

Long-Term Outcome after En Bloc Resection of Non–Small-Cell Lung Cancer Invading the Pulmonary Sulcus and Spine Stéphane Collaud, MD, MSc, Thomas K.

Surgical treatment is decisive for outcome in chondrosarcoma of the chest wall: A population-based Scandinavian Sarcoma Group study of 106 patients Björn.

The effect of regionalization on outcome in pulmonary lobectomy: A Canadian national study Christian J. Finley, MD, MPH, Anna Bendzsak, MD, George Tomlinson,

Long-Term Outcome After Resection of Non-Small Cell Lung Cancer Invading the Thoracic Inlet Stéphane Collaud, MD, MS, Tiago Machuca, MD, PhD, Olaf Mercier,

Pleomorphic carcinoma of the lung: A surgical outcome

Pulmonary hypertension in valve disease: A beast of the past?

Adoption of pleurectomy and decortication for malignant mesothelioma leads to similar survival as extrapleural pneumonectomy Hasan Fevzi Batirel, MD,

Centers for Disease Control “increased-risk” organ donor: Not so risky? Francis D. Pagani, MD, PhD The Journal of Thoracic and Cardiovascular Surgery

Sleeve lung resection for lung cancer: Analysis according to the type of procedure Kazumichi Yamamoto, MD, Yoshihiro Miyamoto, MD, Akihiro Ohsumi, MD,

Skinning the cat: Another wrinkle for T-tube insertion

How should we treat air leaks?

What is the best approach for surgery of malignant pleural mesothelioma? It is to put our efforts into obtaining trustworthy evidence for practice Tom.

Timing of surgery for pulmonary embolism: An evolving paradigm

The lord of the rings Antonio Miceli, MD, PhD

Treatment of the Elderly When Cure is the Goal: The Influence of Age on Treatment Selection and Efficacy for Stage III Non-small Cell Lung Cancer Linda.

Franco Stella, MD, PhD, Francesco Petrella, MD

Support Your Specialty

Innovation and science: The future of valve design

It's not “just a shunt” but sometimes it should be…

Bartley P. Griffith, MD, FACS, FRCS

Experience from an American Association for Thoracic Surgery Foundation for Thoracic Surgery Training Fellowship: Lung transplantation in Toronto General.

Valerie W Rusch, MD, Ennapadam S Venkatraman, PhD

Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: Results in 663 patients Raja.

Patterns of Failure, Toxicity, and Survival after Extrapleural Pneumonectomy and Hemithoracic Intensity-Modulated Radiation Therapy for Malignant Pleural.

Referral Patterns for Adjuvant Chemotherapy in Patients with Completely Resected Non-small Cell Lung Cancer Farrah Kassam, MD, Frances A. Shepherd, MD,

Get it right the first time

Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD

A randomized comparison of different ventilator strategies during thoracotomy for pulmonary resection Andrew D. Maslow, MD, Todd S. Stafford, MD, Kristopher.

Are discordant positron emission tomography and pathological assessments of the mediastinum in non–small cell lung cancer significant? Daniel J. Tandberg,

Induction chemoradiotherapy (carboplatin-taxane and concurrent 50-Gy radiation) for bulky cN2, N3 non–small cell lung cancer Hiroyasu Yokomise, MD, Masashi.

A case of chest wall angiosarcoma associated with breast implants

The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: Implications for revision of the.

Historical perspectives of The American Association for Thoracic Surgery: F. Griffith Pearson (1926–) Andrew Pierre, MD, Vivek Rao, MD, PhD, Shaf Keshavjee,

Marc Licker, MD, John Diaper, RA

We are the company we keep: The importance of the tumor microenvironment Sai Yendamuri, MD, FACS The Journal of Thoracic and Cardiovascular Surgery

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Patients with unbalanced atrioventricular canal defects can undergo the Fontan operation with good outcomes Sitaram M. Emani, MD The Journal of Thoracic.

Functional tricuspid pathology: To treat or not to treat

Risk Factors for Major Complications After Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma Marc de Perrot, MD, Karen McRae, MD, Masaki.

A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma Valerie W. Rusch, MDa, Kenneth.

Improved survival with pulmonary metastasectomy: An analysis of 1720 patients with pulmonary metastatic melanoma Rebecca P. Petersen, MD, MSc, Steven.

Positron emission tomography predicts survival in malignant pleural mesothelioma Raja M. Flores, MD, Timothy Akhurst, MD, Mithat Gonen, PhD, Maureen Zakowski,

Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural.

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

The future of cardiac surgery training: A survival guide

The continuing challenge of congenital heart disease in China

Raja M. Flores, MD The Journal of Thoracic and Cardiovascular Surgery

“The more things change…”: The challenges ahead

Toward a more rational approach in treating type B aortic dissection

Ryan R. Davies, MD The Journal of Thoracic and Cardiovascular Surgery

Preoperative PFTs: The answer is blowing in the wind

Initial Analysis of the International Association For the Study of Lung Cancer Mesothelioma Database Valerie W. Rusch, MD, Dorothy Giroux, Catherine.

European Society of Thoracic Surgeons preoperative mediastinal staging guidelines: From face validity to external validity Alessandro Brunelli, MD The.

Journal changes and initiatives

Marcelo Cypel, MD, MSc, Jonathan C

Proceed with caution: The importance of surveillance in patients with pathologic complete response after chemoradiation therapy plus surgery for esophageal.

Deciding how much to pay for effective care

Presentation transcript:

Accelerated hemithoracic radiation followed by extrapleural pneumonectomy for malignant pleural mesothelioma Marc de Perrot, MD, MSc, Ronald Feld, MD, Natasha B. Leighl, MD, Andrew Hope, MD, Thomas K. Waddell, MD, PhD, Shaf Keshavjee, MD, B.C. John Cho, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 151, Issue 2, Pages 468-475 (February 2016) DOI: 10.1016/j.jtcvs.2015.09.129 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Consort diagram showing the flow of patients through the study. SMART, Surgery for mesothelioma after radiation therapy. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 468-475DOI: (10.1016/j.jtcvs.2015.09.129) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Overall survival as an intention-to-treat analysis for all 62 patients who started accelerated hemithoracic radiation therapy as part of the SMART protocol between November 2008 and October 2014. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 468-475DOI: (10.1016/j.jtcvs.2015.09.129) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Overall survival (A) and disease-free survival (B) according to histological subtype in 56 treatment-naïve patients with cT1-3N0M0. Six patients with tumor extending to the chest wall on preoperative CT (cT4N0M0; n = 2), evidence of mediastinal lymph node involvement on PET scan (cT3N2M0; n = 2), or undergoing SMART after completing chemotherapy (n = 2) were excluded from this analysis. DFS, disease free survival. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 468-475DOI: (10.1016/j.jtcvs.2015.09.129) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Overall survival (A) and disease-free survival (B) in previously untreated cT1-3N0M0 patients with epithelial disease according to nodal status on final pathology. DFS, Disease free survival. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 468-475DOI: (10.1016/j.jtcvs.2015.09.129) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Surgery for mesothelioma after radiation therapy. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 468-475DOI: (10.1016/j.jtcvs.2015.09.129) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions