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Adoption of pleurectomy and decortication for malignant mesothelioma leads to similar survival as extrapleural pneumonectomy  Hasan Fevzi Batirel, MD,

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Presentation on theme: "Adoption of pleurectomy and decortication for malignant mesothelioma leads to similar survival as extrapleural pneumonectomy  Hasan Fevzi Batirel, MD,"— Presentation transcript:

1 Adoption of pleurectomy and decortication for malignant mesothelioma leads to similar survival as extrapleural pneumonectomy  Hasan Fevzi Batirel, MD, PhD, Muzaffer Metintas, MD, Hale Basak Caglar, MD, Guntulu Ak, MD, Perran Fulden Yumuk, MD, Bedrettin Yildizeli, MD, Mustafa Yuksel, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 151, Issue 2, Pages (February 2016) DOI: /j.jtcvs Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 A, Survival curve of 130 patients. Overall median survival was 17.8 months (95% CI, ) and 2- and 5-year survival rates were 32% (95% CI, 28%-37%) and 14% (95% CI, 10%-19%), respectively. B, Survival comparison between the 2 time periods (group 1 [March 2003-July 2011] vs group 2 [August 2011-June 2014]). Overall median survivals and 2-year survival rates were 15.6 months (95% CI, ) and 32% (95% CI, 26%-37%) versus 19.6 months (95% C,I ) and 33% (95% CI, 26%-40%), respectively (P = .34). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 A, Survival comparison of patients with epithelioid and nonepithelioid histology. Median survival and 2-year survival rates were 19.1 months (95% CI, ) and 39% (95% CI, 34%-44%) versus 14.2 months (95% CI, ) and 17% (95% CI, 10%-24%), respectively (P = .039). B, Survival comparison of patients with no lymph node metastasis (N0), extrapleural lymph node metastasis (N2), and unknown lymph node status (Nx). Median survival and 2-year survival rates were 23.4 months (95% CI, ) and 46% (95% CI, 39%-53%) versus 7.1 months (95% CI, ) and 22% (95% CI, 13%-31%) versus 11.9 months (95% CI, ) and 19% (95% CI, 13%-25%), respectively (P = .012). C, Survival comparison of patients with only surgery, bimodality treatment, and trimodality treatment. Median survival and 2-year survival rates were 2.5 months (95% CI, ) and 0% versus 14.3 months (95% CI, ) and 29% (95% CI, 23%-35%) versus 26 months (95% CI, 18-34) and 55% (95% CI, 46%-63%), respectively (P < .001). D, Survival comparison of patients who underwent extrapleural pneumonectomy, pleurectomy, and diagnostic interventions (eg, video-assisted thoracoscopic surgery). Median survival and 2-year survival rates were 18.3 months (95% CI, ) and 35% (95% CI, 28%-43%) versus 14.6 months (95% CI, ) and 35% (95% CI, 29%-42%) versus 11.1 months (95% CI, ) and 22% (95% CI, 12%-31%), respectively (P = .14). EPP, Extrapleural pneumonectomy; VATS, video-assisted thoracoscopic surgery; Dx, diagnostic interventions. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

4 Extrapleural pneumonectomy and pleurectomy and decortication result in the same survival rate in patients with malignant pleural mesothelioma. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions


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