Lack of KRAS and BRAF Mutation in Renal Cell Carcinoma

Slides:

Advertisements

Similar presentations

Urothelial Bladder Carcinoma With Choriocarcinomatous Differentiation Presenting With a False-Positive Pregnancy Test Babak Rajabi, MD, Oscar B. Goodman,

Advertisements

Volume 2, Issue 3, Pages (May 2014)

The Origin of the Bone Scan as a Tumour Marker in Prostate Cancer

Response to Nivolumab in a Patient With Metastatic Clear Cell Renal Cell Carcinoma and End-stage Renal Disease on Dialysis Maria I. Carlo, Darren R.

Volume 63, Issue 2, Pages (February 2013)

Volume 55, Issue 6, Pages (June 2009)

Volume 63, Issue 6, Pages (June 2013)

Determination of vhl Gene Mutations in Sporadic Renal Cell Carcinoma

Potential and Limitations of Diffusion-Weighted Magnetic Resonance Imaging in Kidney, Prostate, and Bladder Cancer Including Pelvic Lymph Node Staging:

Volume 51, Issue 1, Pages (January 2007)

Volume 63, Issue 4, Pages (April 2013)

Bilateral Renal Mass Suggestive of Cancer

Comprehensive Mutation Analysis of the TERT Promoter in Bladder Cancer and Detection of Mutations in Voided Urine Carolyn D. Hurst, Fiona M. Platt, Margaret.

Volume 52, Issue 3, Pages (September 2007)

Histologic Grading of Noninvasive Papillary Urothelial Neoplasms

Volume 53, Issue 5, Pages (May 2008)

BRAF Mutations in Metanephric Adenoma of the Kidney

Volume 59, Issue 1, Pages (January 2011)

Volume 71, Issue 6, Pages e171-e172 (June 2017)

Let the Games Begin (with EAU Approval)

Volume 64, Issue 3, Pages (September 2013)

Prostate Cancer Epidemic in Sight?

Kathie Alexina Wong, Mark Wass, Kay Thomas European Urology

Daily Administration of Phosphodiesterase Type 5 Inhibitors for Urological and Nonurological Indications Anthony J. Bella, Ling X. DeYoung, Mussa al-Numi,

The Importance of Transurethral Resection in Managing Patients With Urothelial Cancer in the Bladder: Proposal for a Transurethral Resection of Bladder.

Measuring the Urologic Iceberg: Design and Implementation of the Boston Area Community Health (BACH) Survey John B. McKinlay, Carol L. Link European.

Volume 54, Issue 4, Pages (October 2008)

Volume 52, Issue 5, Pages (November 2007)

Volume 70, Issue 3, Pages (September 2016)

Prostate Cancer Detection: A View of the Future

CEACAM1: A Novel Urinary Marker for Bladder Cancer Detection

Cost Effectiveness of Nivolumab in Advanced Renal Cell Carcinoma

Volume 66, Issue 5, Pages (November 2014)

Volume 68, Issue 1, Pages (July 2015)

On the Origin of Syn- and Metachronous Urothelial Carcinomas

Volume 60, Issue 5, Pages (November 2011)

Shaheen Alanee, Kasmintan Schrader, Kenneth Offit European Urology

International Society of Urological Pathology Grading and Other Prognostic Factors for Renal Neoplasia Brett Delahunt, John R. Srigley, Lars Egevad,

Volume 56, Issue 6, Pages (December 2009)

Prostate Cancer Epidemic in Sight?

James N. Armitage, Stuart O. Irving, Neil A. Burgess European Urology

Volume 50, Issue 3, Pages (September 2006)

Volume 61, Issue 6, Pages (June 2012)

Volume 74, Issue 3, Pages (September 2018)

The Origin of the Bone Scan as a Tumour Marker in Prostate Cancer

Volume 51, Issue 5, Pages (May 2007)

Neoplasia of the Kidney—a Rare Event During Pregnancy

Shifting Paradigms for High-grade Prostatic Intraepithelial Neoplasia

Tillmann Loch, Pat Fox Fulgham European Urology

The Economic Costs of Overactive Bladder in Germany

Volume 46, Issue 6, Pages (December 2004)

Karl-Dietrich Sievert, Bastian Amend, Arnulf Stenzl European Urology

TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential Liang Cheng, Rodolfo Montironi,

Is Simple Enucleation a Minimal Partial Nephrectomy Responding to the EAU Guidelines’ Recommendations? Vincenzo Ficarra, Antonio Galfano, Stefano Cavalleri

Volume 50, Issue 5, Pages (November 2006)

Volume 55, Issue 6, Pages (June 2009)

CyberKnife in the Treatment of Prostate Cancer: A Revolutionary System

Volume 55, Issue 6, Pages (June 2009)

Testicular Cancer Variations in Time and Space in Europe

Volume 63, Issue 2, Pages (February 2013)

High Frequency of Loss of Heterozygosity on Chromosome Region 9p21–p22 but Lack of p16INK4a/p19ARF Mutations in Greek Patients with Basal Cell Carcinoma.

Sergio Bracarda European Urology Supplements

European Urology is “Your” Journal

Clinical Management of Patients Receiving Tyrosine Kinase Inhibitors for Advanced Renal Cell Carcinoma Jan Roigas European Urology Supplements Volume.

Annika Berntsen, Poul F. Geertsen, Inge Marie Svane European Urology

Joaquim Bellmunt European Urology Supplements

Volume 80, Issue 7, Pages (October 2011)

Jan Roigas European Urology Supplements

Pathology and Molecular Pathogenesis of Renal Cell Carcinoma

Volume 51, Issue 5, Pages (May 2007)

Presentation transcript:

Lack of KRAS and BRAF Mutation in Renal Cell Carcinoma S. Gattenlöhner, B. Etschmann, H. Riedmiller, H.-K. Müller-Hermelink European Urology Volume 55, Issue 6, Pages 1490-1491 (June 2009) DOI: 10.1016/j.eururo.2009.02.024 Copyright © 2009 European Association of Urology Terms and Conditions

Fig. 1 Morphologic changes and results of KRAS mutation analyses in a case of a urothelial carcinoma of the renal pelvis (a; arrow indicates a glomerulum of the renal tissue adjacent to the infiltrating carcinoma) with detection of the KRAS mutation G12D (inset, arrowhead), whereas in a classic clear cell carcinoma (b; asterisk indicates blood vessel infiltration), representative of all conventional renal cell carcinomas investigated, no KRAS mutation was found (inset). Images were produced with a BX50 microscope (Olympus, Hamburg, Germany) and a DP50 digital camera with DP-Soft 5.0 software (Olympus, Hamburg, Germany). European Urology 2009 55, 1490-1491DOI: (10.1016/j.eururo.2009.02.024) Copyright © 2009 European Association of Urology Terms and Conditions