1. Comprehensive Mutation Analysis of the TERT Promoter in Bladder Cancer and Detection of Mutations in Voided Urine 
Carolyn D. Hurst, Fiona M. Platt, Margaret A. Knowles 
European Urology 
Volume 65, Issue 2, Pages (February 2014)
DOI: /j.eururo
Copyright © 2013 European Association of Urology Terms and Conditions

2. Fig. 1
Detection of TERT promoter mutations in bladder tumours using a combination of SNaPshot analysis and Sanger sequencing. SNaPshot detection of (A) −57 base pairs (bp) (T>G; A>C on reverse strand) and (B) −124bp (G>T) mutations in bladder tumours. Somatic mutation status was confirmed by SNaPshot analysis of matched blood samples. Electropherograms of DNA sequencing results for the same samples are shown adjacent to SNaPshot profiles. (C) Mutations detected by Sanger sequencing of the TERT core promoter region and confirmation of somatic status in matched blood samples. (D) SNaPshot analysis of voided urine samples detected −124bp and −146bp mutations. SNaPshot profiles for the corresponding tumour and blood samples are also shown. Orange peaks (s) represent the internal Genescan-120LIZ size standards.
European Urology  , DOI: ( /j.eururo )
Copyright © 2013 European Association of Urology Terms and Conditions

3. European Urology 2014 65, 367-369DOI: (10.1016/j.eururo.2013.08.057)
Copyright © 2013 European Association of Urology Terms and Conditions

4. European Urology 2014 65, 367-369DOI: (10.1016/j.eururo.2013.08.057)
Copyright © 2013 European Association of Urology Terms and Conditions

5. European Urology 2014 65, 367-369DOI: (10.1016/j.eururo.2013.08.057)
Copyright © 2013 European Association of Urology Terms and Conditions