Immunoengineering: How Nanotechnology Can Enhance Cancer Immunotherapy

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Immunoengineering: How Nanotechnology Can Enhance Cancer Immunotherapy Michael S. Goldberg Cell Volume 161, Issue 2, Pages 201-204 (April 2015) DOI: 10.1016/j.cell.2015.03.037 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Applications of Nanotechnology Clockwise from bottom left: nanocarriers can be used to (1) deliver cancer vaccine antigens and adjuvants to dendritic cells, (2) stimulate T cells directly as artificial antigen presenting cells, (3) concentrate immunostimulatory compounds in the immunosuppressive tumor microenvironment, and (4) deliver supportive drugs to T cells in the circulation. (Image credit to Mohammad H. Saleh.) Cell 2015 161, 201-204DOI: (10.1016/j.cell.2015.03.037) Copyright © 2015 Elsevier Inc. Terms and Conditions