Akos Varga-Szemes, MD, PhD, U. Joseph Schoepf, MD, Laura S

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Presentation transcript:

A Rare Case of Intrapulmonary Ewing Sarcoma Presenting with Left Atrial Tumor Thrombus Akos Varga-Szemes, MD, PhD, U. Joseph Schoepf, MD, Laura S. Spruill, MD, PhD, Pal Suranyi, MD, PhD Journal of Thoracic Oncology Volume 10, Issue 7, Pages 1120-1122 (July 2015) DOI: 10.1097/JTO.0000000000000428 Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Representative chest radiograph (A, anteroposterior view), CT (B and C, coronal and four-chamber views), PET-CT (D–G, axial and coronal views), echocardiography (H, four-chamber view), and cardiac MRI (I and J, coronal and four-chamber views) images are shown. CT, computed tomography; PET, positron emission tomography; MRI, magnetic resonance imaging. Journal of Thoracic Oncology 2015 10, 1120-1122DOI: (10.1097/JTO.0000000000000428) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Photomicrographs of the H&E-stained cell-block sample (upper panel, ×40 magnification) and Papanicolaou-stained bronchoscopic cytology sample (bottom panel, ×40 magnification) are shown. The H&E slide demonstrates a “small round blue cell” tumor with dark nuclei and minimal cytoplasm consistent with Ewing sarcoma cells. The Papanicolaou-stained slide shows better morphology and nuclear characteristics with central nucleoli and a rare mitosis. The characteristic cytologic finding in Ewing sarcomas is a dimorphic cell population; one being larger with a more pale nucleus (black arrow, pink/clear vacuoles in the pale cytoplasm) and the second with smaller size and darker nucleus (surrounding the pale cells).3 H&E, hematoxilyn–eosin. Journal of Thoracic Oncology 2015 10, 1120-1122DOI: (10.1097/JTO.0000000000000428) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions