Multiple-dose and double-dose versus single-dose administration of methotrexate for the treatment of ectopic pregnancy: a systematic review and meta-analysis 

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Presentation transcript:

Multiple-dose and double-dose versus single-dose administration of methotrexate for the treatment of ectopic pregnancy: a systematic review and meta-analysis  Chun Yang, Jing Cai, Yuhong Geng, Ying Gao  Reproductive BioMedicine Online  Volume 34, Issue 4, Pages 383-391 (April 2017) DOI: 10.1016/j.rbmo.2017.01.004 Copyright © 2017 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 PRISMA four-phase flow diagram of search yield, screening and inclusion steps. Reproductive BioMedicine Online 2017 34, 383-391DOI: (10.1016/j.rbmo.2017.01.004) Copyright © 2017 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Risk of bias graph (A) and risk of bias summary (B) based on review authors' judgments about each risk of bias item. Reproductive BioMedicine Online 2017 34, 383-391DOI: (10.1016/j.rbmo.2017.01.004) Copyright © 2017 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Meta-analysis results of overall success rates. Reproductive BioMedicine Online 2017 34, 383-391DOI: (10.1016/j.rbmo.2017.01.004) Copyright © 2017 Reproductive Healthcare Ltd. Terms and Conditions

Figure 4 Meta-analysis results of incidence of side-effects. Reproductive BioMedicine Online 2017 34, 383-391DOI: (10.1016/j.rbmo.2017.01.004) Copyright © 2017 Reproductive Healthcare Ltd. Terms and Conditions