1. Clinical benefit using sperm hyaluronic acid binding technique in ICSI cycles: a systematic review and meta-analysis 
Ronit Beck-Fruchter, Eliezer Shalev, Amir Weiss 
Reproductive BioMedicine Online 
Volume 32, Issue 3, Pages (March 2016)
DOI: /j.rbmo
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2. Figure 1 Study selection process.
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3. Figure 2
Fertilization rate for conventional intracytoplasmic sperm (ICSI) injection versus hyaluronic acid selected spermatozoa ICSI. Relative risk (RR) of fertilization rate (RR 1.02, 95% CI 0.99 to 1.06) (test for heterogeneity, Cochran's Q = 13.25, df = 7 P = 0.066, I2 = 47%, random effect model).
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4. Figure 3
Clinical pregnancy rate for conventional intracytoplasmic sperm injection (ICSI) versus hyaluronic acid selected spermatozoa ICSI. Relative risk (RR) of pregnancy rate (RR 1.10, 95% CI 0.93 to 1.30; P = 0.129) (test for heterogeneity, Cochran's Q = 3.23, df = 3, P = 0.358, I2 = 7%, random effects model).
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5. Figure 4
Cleavage rate conventional ICSI versus hyaluronic acid selected spermatozoa intracytoplasmic sperm injection (ICSI). Relative risk (RR) of cleavage rate (RR 0.94, 95% CI 0.91 to 0.97; P < ) (test for heterogeneity, Cochran's Q = 2.20, df = 2, P = 0.333, I2 = 9%, random effects model).
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6. Figure 5
Proportion of top quality embryos conventional intracytoplasmic sperm injection (ICSI) versus hyaluronic acid selected spermatozoa ICSI. Relative risk (RR) of top quality embryo (RR 1.53, 95% CI 1.26 to 1.86; P < ) (test for heterogeneity, Cochran's Q = 0.096, df = 1, P = 0.757, I2 = 0%, random effects model).
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7. Figure 6
Implantation rate for conventional ICSI versus hyaluronic acid selected spermatozoa intracytoplasmic sperm injection (ICSI). Relative risk (RR) of implantation (RR 1.34, 95% CI: 1.04 to 1.72; P = 0.024) (test for heterogeneity, Cochran Q = 1.54, df = 2, P = 0.462, I2 = 0%, random effects model).
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8. Figure 7
Spontaneous abortion rate for ICSI versus hyaluronic acid selected spermatozoa ICSI. Relative risk (RR) of spontaneous abortion (RR 0.89, 95% CI 0.45 to 1.74; P = 0.734) (test for heterogeneity, Cochran's Q = 1.39, df = 2, P = 0.5, I2 = 0%, random effects model).
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9. Figure 8
Live birth rate for conventional intracytoplasmic sperm injection (ICSI) versus hyaluronic acid selected spermatozoa ICSI. Relative risk (RR) of live birth (RR 1.09, 95% CI 0.82 to 1.46; P = 0.563) (test for heterogeneity, Cochran's Q = 1.46, df = 2, P = 0.482, I2 = 0%, random effects model).
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