Jennie Yoost MD, MSc Assistant Professor

Slides:



Advertisements
Similar presentations
IUD Safety Research has proven IUDs to be safe and effective Research has proven IUDs to be safe and effective Elements of high quality care: appropriate.
Advertisements

Adolescents and Long-Acting Reversible Contraception (LARC)
What’s New in Adolescent Contraception? Rachel S-D Fortune, MD, FAAP Medical Director, Newport Academy.
Contraception. What is it? Contraception is any method or technique used to prevent pregnancy Contraception can come in many different forms.
Session I, Slide #11 Levonorgestrel (LNG) Emergency Contraceptive Pills Session I: Characteristics of LNG Emergency Contraceptive Pills.
Are you up with the LARCs? Dr Christine Roke National Medical Advisor, Family Planning March 2011.
Birth Control: what works best for YOU? Slides adapted from Ruth Lesnewski MD; FMDRL.org Katy Kropf DO Heritage College of Osteopathic Medicine November.
Hormonal and Surgical Contraception
Contraceptive Options for Women and Couples with HIV Intrauterine Device (IUD or IUCD) Copper T-380A.
Contraceptive Information. Is the RISK worth it? Risk Avoidance Risk Avoidance This means that there is no chance you would be impacted by sex This means.
CONTRACEPTION. Who needs contraception?  62 million U.S. women in childbearing years (15-44)  Of these 7 out of 10 are sexually active and do not want.
Journal #34 Birth Control List all the methods of birth control you can think of.
Session I: Characteristics of IUDs
Contraception & Teens: Providing the FACTS!. Contraception: contra – against ception – creation.
Emergency Contraception Laurie Hornberger, MD, MPH Assistant Professor of Pediatrics University of Missouri, Kansas City.
Safe Sex & Birth Control Options. Making the decision Difficult decision When is the time right? Are you ready? What steps should you take to protect.
Contraceptives What you NEED to KNOW…
Call from Anonymous Foundation Remove financial barriers to most effective long-term reversible methods –Promote LARC use Provide no-cost contraception.
Levonorgestrel (LNG) Emergency Contraceptive Pills Session I: Characteristics of LNG Emergency Contraceptive Pills.
Contraception. Contraceptive effectiveness Sterilization Sterilization Estrogen-Progestin pills Estrogen-Progestin pills Depo-Provera Depo-Provera Male.
Contraception © Robert J. Atkins, Ph.D.. What are my chances of getting pregnant without contraceptives? No method = 85% chance of pregnancy over a.
Contraception. Contraceptive effectiveness Sterilization Sterilization Estrogen-Progestin pills Estrogen-Progestin pills Depo-Provera Depo-Provera Male.
Use of Long Acting Reversible Contraceptives (LARC) in Job Corps
Amber Anderson.   1. Describe the three different types of IUDs Used for Contraception in the U.S.  2. Identify Patients in which IUDs can be inserted.
Human Sexuality PERSONAL DEVELOPMENT AND CAREER PLANNING 9.
A Comprehensive Understanding of Contraceptives July 8, 2015.
This content is copyrighted by Upstream USA™ Please do not distribute Questions?
Adolescent Contraception
How many couples out of 100 will get pregnant if they have unprotected sex for a year? Answer: Birth Control.
What is pelvic inflammatory disease (PID)? Pelvic inflammatory disease (PID) is an infection in the female reproductive organs. Normally, the cervix prevents.
Who Needs Protection?. A look at effectiveness, how it works, how often it needs to be taken, approximate cost, prescription needed and STI protection…
Birth Control Methods.
Progestogen-only contraception
Richland County Health Department
Contraception: Old and New
Family Planning
Contraception Chapter 6.
Family Planning Methods
Combined Oral Contraceptives
Larc Quiz!.
Contraception Chapter 6.
Senior Health Mrs. Clark
Contraception IUC’s, Sterilization.
Contraception Lecture by Dr.Mohammed Sharique Ahmed Quadri
Abstinence Behavioral 0% failure rate
Choosing a contraception that’s right for u
A Clinician’s Guide to LARC
NOTES – UNIT 11 part 4: Birth Control
Choosing a contraception that’s right for u
Contraception.
Session II: Who Can and Cannot Use IUDs?
Session III: Providing IUDs
Session I: Characteristics of IUDs
Birth Control and Contraception
Chapter 62 Birth Control 1.
Birth Control Methods.
Special Issues of Women’s Health Care and Reproduction
CONTRACEPTION.
Contraception Chapter 6.
Contraception Chapter 6.
Post Abortion Contraception
EMERGENCY CONTRACEPTION SHumi Negesse, MD Assistant Professor, Adama hospital medical college Department of OBSTETRICS AND GYNECOLOGY.
Objectives Describe the types of Intrauterine Devices (IUDs)
Session III: Providing IUDs
Session I: Characteristics of IUDs
Presentation transcript:

Teens and Contraception: New Approaches for Improved Compliance and Decreasing Teen Pregnancy Jennie Yoost MD, MSc Assistant Professor Pediatric and Adolescent Gynecology Marshall University Department of OBGYN

LEARNING OBJECTIVES Understand the mechanism of action and safety profile of different long acting reversible contraceptives including the subdermal implant and levonorgestrel intrauterine devices. Understand the spectrum of contraceptives available and continuation rates of different methods among teenage users. Understand the noncontraceptive benefits to using different methods of contraception. Understand use, access, and mechanism of action of Emergency Contraception.

Case #1 14 year old female presents with her mom. She started menses age 11. Mom is interested in discussing birth control. The girl is not sexually active. Mom feels she “has a good head on her shoulders” and makes good decisions. She worries about some of her friends, and wants her started on birth control “just in case”.

Case #2 15 year old female presents for vaginal discharge. She has been sexually active since age 12, and has had a total of 6 partners since that time. She took birth control pills for a few months, but not using anything at this time. Pregnancy test is negative in the office. You ask if she is interested in birth control. She reports that she is, but “just has a hard time remembering it.” What do you offer her?

WHAT ARE OPTIONS FOR TEENS? SAME OPTIONS AS ADULTS! Pills Patch Ring Injection Intrauterine Device Subdermal Implant

Abstinence: It is important. It is encouraged. It can be secondary. It only works if you are abstinent

Are teens really “doin’ it”? Youth Risk Behavioral Survey 2011 45.6% sexually active 4% report sexual debut before age of 13. (7% among AA) 13% > 4 sexual partners 53% report condom use 22.6% OCP use 7.5% other methods

The problem of unintended pregnancy 6.7 million pregnancies per year in the US 50% are unintended Among 15-19 year olds: 82% unintended 2010 US adolescent birth rate 34.2/1000 2007 US adolescent birth rate 42.5/1000

How do we compare to the rest of the world?

Variations within the US: among states (2010) GOOD: New Hamp 15.7 Massachusetts 17.2 Vermont 17.9 BAD: Texas 52.2 Arkansas 52.5 New Mexico 53 Mississippi 55 WV (44.8) #43

Teens and birth control compliance: METHOD USE FAILURE: Perfect Use FAILURE: Typical Use Continuation at 12 months Pills Take one pill daily 0.3% 9% 33-52% Patch Place one patch weekly 25-50% Ring Place one ring monthly 31%* Injection Injection by health provider every 3 months 0.2% 6% 27-55% Pills are overall the most common choice for teens. 50% of adolescents report missed pills during a given cycle

What is a LARC? Long Acting Reversible Contraception Intrauterine Device Progesterone containing (Mirena®, Skyla®) Copper T (Paragard®) Subdermal Implant Nexplanon®

LARCs- a good option for teens! Copper IUD Paragard® No hormones Effective for up to 10 years Placed by a simple procedure Can be done under sedation Mechanism of Action Copper ions inhibit sperm motility Inhibition of sperm capacitation (ability of sperm to fertilize an ovum) Sterile inflammatory reaction of endometrium (phagocytosis of sperm) May cause increased menstrual bleeding

LARCs- a good option for teens! Levonorgestrel IUDs Mechanism of Action Increased cervical mucous Decreased tubal motility/ change in tubal fluid Alteration of endometrium Ovulatory inhibition Mirena® 20mcg/day levonorgestrel Lasts 5 years Skyla® 14mcg/day levonorgestrel Lasts 3 years Smaller dimensions Placed by a simple procedure Can be done under sedation

Levonorgestrel IUDs Noncontraceptive Benefits Contraindications Decreased menstrual bleeding Amenorrhea Improved dysmenorrhea Local action No medication interaction Use in girls with medical comorbidities Contraindications Pregnant (too late!) Active PID or puerperal or postabortion sepsis Current STDs Undiagnosed vaginal bleeding Malignancy of genital tract Known uterine anomaly or distortion of uterine cavity

LARCS- a good option for teens! Subdermal Implant Nexplanon™ 68mg etonogestrel Single rod Effective for at least 3 years Procedure Inserted subdermally in groove just below biceps Can be placed at initial visit Mechanism of Action Ovulation inhibition Increased cervical mucous Endometrial atrophy

Nexplanon®

LARCs- a good option for teens! METHOD FAILURE: Perfect Use Typical Use Levonorgestrel IUD 0.2% Subdermal Implant 0.05%

Don’t Believe Me? ACOG: “top tier methods of contraception including IUDs and implants should be considered as first line choices for adolescents” CDC/WHO: Subdermal implants= Category I “no restriction” IUD=Category II “advantages outweigh theoretically or proven risk”

“But my friend’s sister’s friend told me that…….”

Lets Look at the Data: Pregnancy Compliance/ Continuation Satisfaction Bleeding patterns Risks

CHOICE study- prospective cohort (St. Louis, Aug 2007-Sept 2011) 9256 patients Risk of pregnancy: Pill/patch/ring= 4.55/100 pt years LARC= 0.27/ 100 pt years Efficacy not altered when stratified for age <21

CHOICE Study Results:

LARCs had 81% continuation at 1 year--- Better than any other non-LARC method!!

LARC- Satisfaction CHOICE study: 75% of patients chose a LARC method 69% of adolescents chose a LARC method Women using LARC methods had highest satisfaction at 1 year follow up Method % Satisfied at 1 year Levonorgestrel IUD 86% Copper IUD 80% Subdermal Implant 78% Injection 54% Pills Ring 52% Patch 42%

Subdermal Implant: What are the risks? Complications are rare (<1%) Infection Hematoma formation Local irritation Expulsion- rare case reports occurring in setting of infection

Subdermal Implant: Bleeding patterns Unscheduled bleeding Can not predict bleeding pattern Abnormal bleeding can lead to discontinuation in 10-14% of patients Meta-analysis (780 women) Evaluated bleeding patterns in first 2 years of use 22% amenorrhea 34% infrequent bleeding (<3 episodes of bleeding) 7% frequent bleeding (>5 episodes of bleeding) 18% prolonged bleeding (≥1 episode lasting >14 consecutive days)

IUD Risks: “This ain’t your Mama’s IUD” Infection: Monofilament string- does not increase risk of pelvic infection WHO clinical trial (23,000 IUD insertions) Risk of PID was same as baseline risk in population without an IUD Increased in first 20 days after insertion (9.7/1000 women-years) From 21 days- 8 years risk 1.4/1000 women years (same as general population)

IUDs and Infection Screen for Gonorrhea and Chlamydia before or at the time of insertion What if GC/CT test comes up positive? TREAT---Do NOT REMOVE IUD Absolute risk of PID is low 0-5% among women with a positive GC/CT test at time of insertion

IUD Risks: Expulsion Partial or complete expulsion from the uterus Skyla: 3.2% (clinical trial- 54 out of 1665) Mirena/Paragard- between 2-10% in first year What to do: Can replace it with another IUD Can change methods

IUD Risks: Perforation Skyla clinical trial: incidence of <0.1% Mirena/Paragard: WHO: <1 per 1000 Dependent on experience of practitioner Insufficient data to demonstate a difference in perforation risk between parous and nulliparous women Only case series exist of difficult removals and laparoscopic removals

IUD: Bleeding patterns Mirena® Most common change is decreased bleeding Average monthly blood loss drops by 90% At 1 year 20-40% amenorrhea Best bleeding profile among all options FDA approved for treatment of heavy menstrual bleeding

IUD Bleeding patterns: Skyla™ First 90 days Second 90 days 1 year 3 years Amenorrhea <1% 3% 6% 12% Infrequent bleeding 8% 19% 20% 22% Frequent bleeding 31% 4% Prolonged bleeding 59% 17% 9% Treatment days 1-28 Treatment days 337-365 Mean # bleeding days 7.3 (±5.6) 2.1 (±2.7) Mean # spotting days 9.2 (±6.1) 3.3 (±3.1)

IUD: Other Myths and Misconceptions Misconception: IUD insertion is painful/difficult in nulliparous Insertion not technically difficult Risk of discomfort (86% report discomfort with insertion) Pre-procedure misoprostol gives no improvement Overall well tolerated Misconception: IUDs must be inserted during menses Can be inserted at any time Menses may make insertion easier Must exclude pregnancy MYTH: IUD causes infertility Fertility returns immediately with removal Prior studies among infertile women showed no correlation with previous IUD use MYTH: IUD causes ectopic pregnancy Lowers risk just as overall risk of pregnancy decreased 0-0.5per 1000 women- years (compared to 3.25-5 in women without) If pregnancy occurs, proportion is higher

Levonorgestrel IUD: Don’t Forget the Benefits!! Use in those with medical contraindications to estrogen Menstrual suppression for physical and developmental disabilities Treatment of heavy menstrual bleeding Treatment of dysmenorrhea (“bad cramps”) Treatment of pelvic pain and endometriosis Dysmenorrhea is leading cause of short-term recurrent school absenteeism

Contraception in Teens: Some final thoughts A pelvic exam is not required for giving an adolescent birth control (IUD is exception) Quick Start is preferred for all methods Discuss concerns/misperceptions at the onset

Case #3 16 year old female presents for routine gyn exam on Monday morning. Sexual history reveals that she is currently not using any hormonal contraceptive method. Had unprotected sex on Saturday night and concerned about her chance of pregnancy. Wants to know what she should do.

Emergency Contraception Plan B One-Step™ - Levonorgestrel 1.5mg FDA approved in 1999 Available over the counter for age ≥17 2011- Dept HHS overturned FDA decision to make OTC without age restriction 4/5/13: Federal court rules emergency contraceptives needs to be sold over the counter 4/30/13: FDA approves morning-after pill without prescription for girls 15 and older

Response to court ruling: American Academy of Pediatrics: “While pediatricians recommend that teens delay sexual activity until they fully understand its consequences, we strongly encourage the use of contraception, including emergency contraception to protect the health of our adolescent patients who are sexually active.” Society of Adolescent Health and Medicine: “Today’s ruling acknowledges clear evidence that EC is a safe and effective method of backup birth control for all women of reproductive age” American College of Obstetricians and Gynecologists: “EC is a safe, effective way to help prevent unintended pregnancy after a contraceptive failure, unprotected sex, or sexual assault. We believe all EC products should be available over the counter.”

Emergency Contraception: What is it? Levonorgestrel 1.5mg Progesterone only medication taken in one dose Decreases risk of pregnancy from 8% to 1-2% after single episode of unprotected sex Can be taken up to 5 days after unprotected intercourse

Emergency Contraception: How does it work? Progesterone Inhibits or delays ovulation May interfere with sperm transport or tubal motility Does not disrupt a pregnancy!!!! X X

Let me repeat….. If you’re already pregnant, it won’t do anything to the existing pregnancy Will not cause an abortion Will not harm a developing embryo.

Emergency Contraception: Who can take it? World Health Organization: Category 1 No restrictions to use Okay for females with contraindications to birth control pills Cardiovascular disease, liver disease, migraines, etc…

Emergency Contraception: When do you take it? No clinical exam or pregnancy test necessary before use Any time unprotected or inadequately protected intercourse occurs Take as soon as possible after event Efficacy decreases with time Still moderately effective when taken up to 5 days after intercourse

Emergency Contraception: What are the side effects? Nausea (18%) Vomiting (4%) Repeat dose if vomiting occurs <2 hours from initial dose Irregular bleeding Menses occurs usually within 1 week before or after expected

Emergency Contraception: Costs approximately $50 Does not protect against subsequent intercourse Does not protect against STDs Need to discuss more effective forms of contraception

References: ACOG Practice Bulletin No. 121: Long-acting reversible contraception: Implants and intrauterine devices. Obstet Gynecol 2011;118:184-96. Committee opinion no. 539: adolescents and long-acting reversible contraception: implants and intrauterine devices. Obstet Gynecol 2012;120:983-8. FINER LB, ZOLNA MR. Unintended pregnancy in the United States: incidence and disparities, 2006. Contraception 2011;84:478-85. KEARNEY MS, LEVINE PB. Why is the teen birth rate in the United States so high and why does it matter? The journal of economic perspectives : a journal of the American Economic Association 2012;26:141-66. YANG Z, GAYDOS LM. Reasons for and challenges of recent increases in teen birth rates: a study of family planning service policies and demographic changes at the state level. J Adolesc Health 2010;46:517- 24. MARTIN JA, HAMILTON BE, VENTURA SJ, et al. Births: final data for 2010. National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System 2012;60:1-70. EDWARDS SM, ZIEMAN M, JONES K, DIAZ A, ROBILOTTO C, WESTHOFF C. Initiation of oral contraceptives--start now! J Adolesc Health 2008;43:432-6. EATON DK, KANN L, KINCHEN S, et al. Youth risk behavior surveillance - United States, 2011. MMWR Surveill Summ 2012;61:1-162.

References: THURMAN AR, HAMMOND N, BROWN HE, RODDY ME. Preventing repeat teen pregnancy: postpartum depot medroxyprogesterone acetate, oral contraceptive pills, or the patch? J Pediatr Adolesc Gynecol 2007;20:61- 5. SUCATO GS, LAND SR, MURRAY PJ, CECCHINI R, GOLD MA. Adolescents' experiences using the contraceptive patch versus pills. J Pediatr Adolesc Gynecol 2011;24:197-203. ZIBNERS A, CROMER BA, HAYES J. Comparison of continuation rates for hormonal contraception among adolescents. J Pediatr Adolesc Gynecol 1999;12:90-4. RUSSO JA, MILLER E, GOLD MA. Myths and misconceptions about long- acting reversible contraception (LARC). J Adolesc Health 2013;52:S14- 21. CARR S, ESPEY E. Intrauterine devices and pelvic inflammatory disease among adolescents. J Adolesc Health 2013;52:S22-8. ROSENSTOCK JR, PEIPERT JF, MADDEN T, ZHAO Q, SECURA GM. Continuation of reversible contraception in teenagers and young women. Obstet Gynecol 2012;120:1298-305. WINNER B, PEIPERT JF, ZHAO Q, et al. Effectiveness of long-acting reversible contraception. N Engl J Med 2012;366:1998-2007. ACOG Practice Bulletin No. 112: Emergency contraception. Obstet Gynecol 2010;115:1100-9.

Thank You!