Ulcerative Colitis Mayo Clinic Proceedings Joseph D. Feuerstein, MD, Adam S. Cheifetz, MD  Mayo Clinic Proceedings  Volume 89, Issue 11, Pages 1553-1563 (November 2014) DOI: 10.1016/j.mayocp.2014.07.002 Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure A, Transverse computed tomogram of the abdomen showing slight indistinctness of the serosa predominantly along the mesenteric side of the cecum and descending colon consistent with active colitis. B, Coronal computed tomogram of the abdomen and pelvis showing pan-colonic mural thickening (black arrow) of colon filled with oral contrast. C, Sigmoid colon with erythema, friability, edema, scattered erosions, and exudates. D, Rectosigmoid biopsy specimen shows basal lymphoplasmacytosis, Paneth cell metaplasia, and crypt architectural distortion with crypt shortening and branching, as well as reduced number of crypts, indicating a chronic component to the colitis. In addition, scattered neutrophils are present within the crypt epithelium, indicating an active component to the colitis. E, High-powered view showing crypt neutrophils. Mayo Clinic Proceedings 2014 89, 1553-1563DOI: (10.1016/j.mayocp.2014.07.002) Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions