Building better therapy for children with acute lymphoblastic leukemia

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Presentation transcript:

Building better therapy for children with acute lymphoblastic leukemia William L. Carroll, Elizabeth A. Raetz Cancer Cell Volume 7, Issue 4, Pages 289-291 (April 2005) DOI: 10.1016/j.ccr.2005.04.003 Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 1 Risk group stratification in pediatric ALL A combination of clinical and biological features of the tumor and host are currently used for risk group stratification. These features include a patient’s age and initial white blood cell count (WBC), genetic features of leukemic blasts, and early treatment response. Therapy is based on the predicted risk of relapse, such that children in lower risk groups receive less intensive treatment than those in higher risk groups. The event-free survival (EFS) rates for patients in different risk groups are shown. Cancer Cell 2005 7, 289-291DOI: (10.1016/j.ccr.2005.04.003) Copyright © 2005 Elsevier Inc. Terms and Conditions