Fundamental Concepts in the Diagnosis of Advanced NSCLC

Patient Case 1 62-Year-Old Woman

Patient Case 1 Chest CT

Patient Case 1 PET Scan

Patient Case 1 (cont)

ACCP Guidelines for Diagnosis

EBUS Best Practice Advice From the Experts

EBUS Best Practice Advice From the Experts (cont)

Advanced Nonsquamous NSCLC Negative for Targetable Mutation

Patient Case 1 (cont) Treatment

Quality of Life

Advanced Squamous NSCLC Negative for a Targetable Mutation

Immunotherapy

Patient Case 2 52-Year-Old Female Nonsmoker

Patient Case 2 (cont)

Epidermal Growth Factor Receptor (EGFR) Mutations in NSCLC

Molecular Testing

Patient Case 2 (cont)

Best Practices for Diagnosis

Multidisciplinary Teams

Differentiating Squamous and Nonsquamous NSCLC

Patient Case 2 (cont)

FDA-Approved EGFR TKIs for NSCLC

Resistance to EGFR TKIs

EGFR Therapy vs Chemotherapy Outcomes

ALK Gene Rearrangements

Other Histologies

Summary

Summary (cont)

Abbreviations

Abbreviations (cont)