A Young Man With Hemoptysis and Cavitary Lung Lesions

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A Young Man With Hemoptysis and Cavitary Lung Lesions Virginia A. Brady, MD, Andrey V. Zinchuk, MD, Mark D. Siegel, MD, FCCP, Jennifer D. Possick, MD  CHEST  Volume 153, Issue 4, Pages e85-e88 (April 2018) DOI: 10.1016/j.chest.2017.09.018 Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 1 Right upper lobe cavitary lesion with associated bronchiectasis and tree-in-bud pattern. CHEST 2018 153, e85-e88DOI: (10.1016/j.chest.2017.09.018) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 2 Resolution of right upper lobe cavity and improvement of bronchiectasis and tree-in-bud changes after 2 months of anti-TB therapy with rifampin, isoniazid, pyrazinamide, and ethambutol. No new pulmonary lesions were identified. CHEST 2018 153, e85-e88DOI: (10.1016/j.chest.2017.09.018) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 3 A, Development of new right lower lobe thick-walled cavitary lesion with surrounding ground-glass opacities while on isoniazid and rifampin; after completing 3 months of anti-TB therapy. There were no new findings in the right upper lobe. B, Hematoxylin and eosin stain of CT-guided lung biopsy of the right lower lobe cavitary lung lesion demonstrating lung parenchyma with an eosinophilic infiltrate. A single structure with a refractile wall, roughly 30 microns in diameter was identified. Image courtesy of Robert Homer, MD, PhD, professor of pathology, Department of Pathology, Yale School of Medicine. CHEST 2018 153, e85-e88DOI: (10.1016/j.chest.2017.09.018) Copyright © 2017 American College of Chest Physicians Terms and Conditions