Coffee Consumption and Risk of Liver Cancer: A Meta-Analysis Susanna C. Larsson, Alicja Wolk  Gastroenterology  Volume 132, Issue 5, Pages 1740-1745 (May 2007) DOI: 10.1053/j.gastro.2007.03.044 Copyright © 2007 AGA Institute Terms and Conditions

Figure 1 Relative risks of liver cancer associated with coffee consumption (per 2 cups/day increment). Squares represent study-specific relative risk estimates (size of the square reflects the study-specific statistical weight, that is, the inverse of the variance); horizontal lines represent 95% CIs; diamonds represent summary relative risk estimates with corresponding 95% CIs. Tests for heterogeneity: all studies, Q = 11.56; P = .17; I2 = 30.8%; cohort studies, Q = 1.74; P = .63; I2 = 0%; case–control studies, Q = 9.28; P = .05; I2 = 36.9%. Gastroenterology 2007 132, 1740-1745DOI: (10.1053/j.gastro.2007.03.044) Copyright © 2007 AGA Institute Terms and Conditions

Figure 2 Relative risks of liver cancer associated with coffee consumption (per 2 cups/day increment), stratified by history of liver disease. Squares represent study-specific relative risk estimates (size of the square reflects the study-specific statistical weight, that is, the inverse of the variance); horizontal lines represent 95% CIs; diamonds represent summary relative risk estimates with corresponding 95% CIs. Tests for heterogeneity: without a history of liver disease, Q = 4.58; P = .21; I2 = 34.6%; with a history of liver disease, Q = 7.00; P = .07; I2 = 57.1%. Gastroenterology 2007 132, 1740-1745DOI: (10.1053/j.gastro.2007.03.044) Copyright © 2007 AGA Institute Terms and Conditions