Drosophila Development: Embryogenesis

Slides:



Advertisements
Similar presentations
Animal Development Drosophila axis formation Part 1: A-P patterning
Advertisements

Animal Development Drosophila axis formation Part 1: A-P patterning
Homeobox Genes Body organisation.
Cell identity and positional information. How does a neuron find its target?
1 * egg: generate the system * larva: eat and grow
Drosophila melanogaster 2.5mm Movie. The Life Cycle 1-2 weeks 36hr 60 hr 12 hr.
Studying Segmentation Mutants in Balanced Stocks.
Lecture 5 Anterior Posterior axis formation: Cell Biology Bicoid is a morphogen.
MCDB 4650 Developmental Genetics in Drosophila
Pattern formation in drosophila Katja Nowick TFome and Transcriptome Evolution
Drosophila – 2 lectures (½ – 1- ½ ) Cleavage View -gastrulation, organogen. frame metamorph. Once we know the embryo, meet the molecules Because this is.
The Genetic Basis of Development
12 The Genetic Control of Development. Gene Regulation in Development Key process in development is pattern formation = emergence of spatially organized.
Chapter 16 The Genetic Basis of Development. Determination is a multistep process Pluripotent embryonic cells MesodermEctoderm Nerve cells Skin cells.
1 * egg: generate the system * larva: eat and grow
Lecture 6 Anterior posterior axis formation-the posterior signal Anterior posterior axis formation-down the hierarchy.
9.17 Generalized model of Drosophila anterior-posterior pattern formation (Part 1)
Embryonic Development & Cell Differentiation. During embryonic development, a fertilized egg gives rise to many different cell types Cell types are organized.
Anterior-posterior patterning in Drosophila
Gradients, cascades, and signaling pathways
I can’t wait to grow up! Laugh now.
6 and 8 November, 2006 Chapter 18 Gene Regulation During Development.
Figure Homologous Pathways Specifying Neural Ectoderm in Protostomes (Drosophila) and Deuterostomes (Xenopus) D/V.
Drosophila dorsal/ventral axis detemination How are different tissue types specified at distinct positions on the embryonic dorsal- ventral axis?
Drosophila dorsal/ventral axis detemination
Chapter 9 - Axis specification in Drosophila Drosophila genetics is the groundwork for _______________l genetics Cheap, easy to breed and maintain Drosophila.
Animal Physiology and Development Insects –3 JCS Lecture Outcome: By the end of this lecture student should have: a)Become aware of the early processes.
Embryonic Development
Chapter 21 The Genetic Basis of Development. Model Organisms.
Chapters 19 - Genetic Analysis of Development: Development Development refers to interaction of then genome with the cytoplasm and external environment.
Drosophila anterior-posterior axis formation during early embryogenesis Genetics Unit Department of Biochemistry
Developmental Biology
Drosophila melanogaster
Major questions in developmental biology Single genome Diverse cell types Totipotent zygote Fate refinement Diverse cell fates Cell commitments are largely.
MATH 499 VIGRE Seminar: Mathematical Models in Developmental Biology
Chapters #5 and #2. Box 4A wild-type fruit fly antennapedia mutant.
Concept 18.4: A program of differential gene expression leads to the different cell types in a multicellular organism.
Human Drosophila C. elegans ~ 24,000 Genes ~ 13,000 Genes ~ 19,000 Genes Mouse ~ 24,000 Genes.
Chapters 47 & 21 Animal Development & The Genetic Basis of Development.
Gap genes also encode TFs They regulate each other’s txn: Ex: Hb represses txn of Kr, helping to refine anterior boundary of Kr expression. They also regulate.
Gene Expression and Development II. Final Exam Sunday, May 27, 8:30-11:30 a.m. Here – SMC A110 Please do course evaluations!
Development and Genes Part 1. 2 Development is the process of timed genetic controlled changes that occurs in an organism’s life cycle. Mitosis Cell differentiation.
PRINCIPLES OF EMBRYONIC DEVELOPMENT © 2012 Pearson Education, Inc.
Chapters 19 - Genetic Analysis of Development:
Objective 7 TSWBat recognize the basic steps on the embryonic development of organisms and the role that gene expression plays in that development.
Comparison of larval and adult Drosophila. Drosophila segmentation genes Gap: Kruppel (Kr),knirps (kni), hunchback (hb), giant (gt),tailless tll), Pair.
Drosophila axis detemination; dorsal/ventral polarity How are the embryonic axes set up? How does the embryonic dorsal-ventral axis get translated into.
LE 21-11a Sperm Molecules of a cytoplasmic determinant Fertilization Nucleus Molecules of another cytoplasmic determinant Unfertilized egg cell Zygote.
Developmental Genetics and Immunogenetics
© 2011 Pearson Education, Inc.
Day Date Reading Topic T 9/3 pp (Ch. 6) C. elegans, model systems, and molecular genetics Watch three Audio/Video.
Animal Development Drosophila axis formation Part 1: A-P patterning
Chapters 19 - Genetic Analysis of Development:
Day Date Reading Topic T 10/15 no class – October Vacation
1 * egg: generate the system * larva: eat and grow
Chapter 21 The Genetic Basis of Development.
Determination commits a cell to its final fate
Developmental Genetics
Developmental Genetics
Animal Development Drosophila axis formation Part 1: A-P patterning
1 * egg: generate the system * larva: eat and grow
Drosophila melanogaster
Establishing positional information along anterior-posterior axis
The Neuron The Brain Embryology Genetics of Development Bio Trivia
Chapters 19 - Genetic Analysis of Development:
CHAPTER 11 The Control of Gene Expression
FORMING THE NOSE VERSUS TAIL OF A FLY
Gene Regulation During Development
Figure 20.1 Sperm and Egg Differ Greatly in Size
Genetics of Axis Specification in Drosophila: Anterior-Posterior Axis Determination Gilbert - Chapter 9.
Presentation transcript:

Drosophila Development: Embryogenesis

Segmental larva organization

Relationship between larval segments and adult structures

Body plan is determined by Maternal-effect and Zygotic-effect Genes

Follicle cells determine assymetric structure of the egg Egg Structure Oogenesis

Posterior Cytoplasmic Structures Determine Germ Cell Fate

A Gradient of Nuclear dorsal transcription factors determines the Dorsal Ventral Axis

Ventrally-located Follicle Cells Determine Nuclear dorsal through toll signalling pathway

Bicoid and Hunchback Gradients Determine Anterior Cell Fates Nanos (NOS) Gradient Determines HB-M gradient

3’ UTR determines localization of bicoid and nanos mRNA

Sequential Induction by Regulatory Proteins Determines and Refines the body plan

GAP gene mRNA localization

Pair-rule Protein Localization

Loss of function mutant phenotypes

Wild Type Fly

Homeotic Mutant

Homeobox Gene Clusters Also Regulate Body Plan in Vertebrates

Anterior to Posterior Expression of HOX genes in developing mouse

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.