Volume 7, Issue 11, Pages R670-R672 (November 1997)

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Presentation transcript:

Volume 7, Issue 11, Pages R670-R672 (November 1997) Circadian clocks Michael H. Hastings Current Biology Volume 7, Issue 11, Pages R670-R672 (November 1997) DOI: 10.1016/S0960-9822(06)00350-2

Figure 1 In this live mouse pup (shown nose towards bottom right), the circadian transcriptional programme has been imaged in real time, by means of the expression of a transgene in which the human c-fos promoter drives expression of a luciferase reporter gene. In this way, the circadian rhythm of c-fos expression in the clock nucleus of the suprachiasmatic nucleus (SCN) has been observed. The bioluminescence in this image results from c-fos expression in the skin. (For more details, see Current Biology 1997, 7:758–766.) Current Biology 1997 7, R670-R672DOI: (10.1016/S0960-9822(06)00350-2)