Myc Target miRs and Liver Cancer: Small Molecules to Get Myc Sick

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Myc Target miRs and Liver Cancer: Small Molecules to Get Myc Sick Marie–Annick Buendia, Ludovic Bourre, Stefano Cairo  Gastroenterology  Volume 142, Issue 2, Pages 214-218 (February 2012) DOI: 10.1053/j.gastro.2011.12.023 Copyright © 2012 AGA Institute Terms and Conditions

Figure 1 Schematic representation of Myc-mediated oncogenesis in developing and adult liver. The yellow thunderbolts, represent genetic, viral or environmental insults. The impact of Myc activation on liver tumor formation is expressed as a ratio between frequency (f) and latency (l). Gastroenterology 2012 142, 214-218DOI: (10.1053/j.gastro.2011.12.023) Copyright © 2012 AGA Institute Terms and Conditions

Figure 2 Overview of the impact of Myc expression on modulation of miRs that determine hepatic cell fate. Gastroenterology 2012 142, 214-218DOI: (10.1053/j.gastro.2011.12.023) Copyright © 2012 AGA Institute Terms and Conditions