Body Mass Index and All-cause Mortality in Chronic Kidney Disease: A Dose–response Meta-analysis of Observational Studies Mehran Rahimlu, MSc, Sakineh.

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Presentation transcript:

Body Mass Index and All-cause Mortality in Chronic Kidney Disease: A Dose–response Meta-analysis of Observational Studies Mehran Rahimlu, MSc, Sakineh Shab-Bidar, PhD, Kurosh Djafarian, PhD Journal of Renal Nutrition Volume 27, Issue 4, Pages 225-232 (July 2017) DOI: 10.1053/j.jrn.2017.01.016 Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Flow chart of literature review and study selection. Journal of Renal Nutrition 2017 27, 225-232DOI: (10.1053/j.jrn.2017.01.016) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 BMI range in the included studies. BMI, body mass index. Journal of Renal Nutrition 2017 27, 225-232DOI: (10.1053/j.jrn.2017.01.016) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Relative risks of total mortality for the highest versus lowest category of body mass index. Diamonds represent study-specific relative risk estimates (size of the square reflects the study-specific statistical weight, i.e., the inverse of the variance); horizontal lines represent 95% CIs; diamond represents the overall relative risk with its 95% CIs. CI, confidence interval; ES, effect size. Journal of Renal Nutrition 2017 27, 225-232DOI: (10.1053/j.jrn.2017.01.016) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 Adjusted relative risk of total mortality associated with BMI in a meta-analysis of published studies, 2003 to 2014 (A), studies on patient with hemodialysis (B), and studies excluding patients with peritoneal (C). Body mass index was modeled with restricted cubic splines in a multivariate random-effects dose–response model. The vertical axis is on a log scale. Long-dashed maroon lines depict 95% confidence intervals (CIs). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.) Journal of Renal Nutrition 2017 27, 225-232DOI: (10.1053/j.jrn.2017.01.016) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions