Vitamin D3 increased ASL antimicrobial activity.

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Presentation transcript:

Vitamin D3 increased ASL antimicrobial activity. Vitamin D3 increased ASL antimicrobial activity. ASL antimicrobial activity assay. (A) ASL antimicrobial activity at baseline and after vitamin D3 (Baseline vs vitamin D mean±SD, 5980±1201 vs 5399±855.8; 95% CI of the difference −1122 to −40.37; *p=0.0365 by paired t-test). (B) ASL antimicrobial activity at baseline and after placebo. Placebo treatment did not increase the ASL antimicrobial activity compared to baseline (baseline vs placebo Mean±SD, 6155±1130 vs 5670±1089; 95% CI of the difference −1170 to 198.5; p=0.1532 by paired t-test). ASL, airway surface liquid; LL-37, human cathelicidin. Luis G Vargas Buonfiglio et al. BMJ Open Resp Res 2017;4:e000211 ©2017 by British Thoracic Society