CIRRHOSIS LIVER Alanoud Aldrsony.

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Presentation transcript:

CIRRHOSIS LIVER Alanoud Aldrsony

Common symptoms Anorexia nausea abdominal discomfort Swelling of the abdomen, legs and ankles Weakness weight loss malaise .

Clinical findings Enlargement of the liver and spleen due to PHTN Ascites Caput medusa Peripheral edema Jaundice Spider nevi in chest or arm GI bleeding Gynecomastia Hypogonadism (testicular atrophy) Kayser-fleischer ring

Nail changes Clubbing Muehrcke's Terry's nails Dupuytren's contracture

DD: -Alcoholic hepatitis -Autoimmune Hepatitis -Hepatitis due to viral (c most commen) -Hepatorenal syndrome -Portal hypertension -Hepatic encephalopathy -Ascites

Investigation CBC Liver function test Kidney function test Tests for hepatitis B and C MRI CT Ultrasound Biopsy

Management Stop alcohol Prednisone and azathioprine - For autoimmune hepatitis Antiviral - For hepatitis B and C Phlebotomy - For hemochromatosis Zinc - For Wilson disease Hepatorenal syndrome: liver transplantation ,iv volume with albumin and fresh frozen plasma. Hepatic encephalopathy: Lactulose and antibiotics . Ascites: sodium restriction, diuretics, large-volume paracentesis .