Neurosurgical management of intractable pain Mohammad.reza akrami M.D.
Pain Acute Chronic Nociceptive Neuropathic
Surgical treatment of intractable pain is not usually the first treatment option Medication Adjuvant therapy Simple nerve block Augmentative ablative
Patient selection for surgical pain therapies
Surgical procedures for trigeminal pain Surgical procedures for nontrigeminal pain
Neurosurgical pain therapies
Augmentative Stimulation Neuroaxial drug infusion Advantages……. safe,adjustable,reversibilty Disadvantages…….expensive ,need to maintenance,life expectancy >3 m
stimulation SCS Main indication is neuropathic pain in limbs FBSS CRPS
Stimulation PNS Cranial PHN Occipital neuralgia When pain is limited to specific nerve Cranial PHN Occipital neuralgia
stimulation DBS Target Thalamus PAG INDICATION TGN FBSS Cancer pains
stimulation MCS INDICATIONS TGN FBSS CANCER PAIN (3M+) MCS vs. DBS
neuroaxial drug infusion Intrathecal/epidural Intraventricular For below the neck pains For above the neck intraven. Effective in both nociceptive and neuropathic pain Expensive and need for maintenance
ablative The last choice 3 site for intervention Peripheral Cheap, less technique demanding ,no need for f/u, feasible in cancers Invasive ,irreversible 3 site for intervention Peripheral Spinal cord intracranial
Sympathectomy visceral pain in cancers limb pain in vasospastic dis Sympathectomy visceral pain in cancers limb pain in vasospastic dis. No good for nonmalignant pain
Neurectomy usually in non functionl limb or amputated limb
Neurectomy
Dorsal rhizotomy and ganglionectomy back, neck ,abdoman no good for functional limb
DREZ lesioning for trunk and limbs in cord inj pains trumatic avulsion of root
cordotomy Target :spinothalamic tract Excellent response 80% Open vs percutaneous No need for f/u Good for cancer
thalamotomy In all types of pain Steriotaxic RF SRS
Singolotomy The last choice When others ineffective Good for cancer pains
hypophysectomy Good relief of hormone responsive cancers pain Specific mechanism of pain relief is unknown Techinques SRS SURGERY