Schematic diagram showing arrangement of thick and thin filaments within the sarcomere. Thick filaments contain myosin, myosin-binding protein C, and titin.

Slides:

Advertisements

Similar presentations

Muscle cells possess contractile filaments containing actin and myosin

Advertisements

Types of Muscle, structure and Function

Structure of Skeletal Muscle Presentation by: Angela Holloman.

Muscle Specialized for: Types:.

Muscular System Chapter 8.

Fig Myofibrils are surrounded by calcium- containing sarcoplasmic reticulum.

Week 1 Click images for hyperlinks!. What is a muscle? Muscles are organs made of muscular and connective tissues, which make up the Muscular System They.

Copyright © 2006 Lippincott Williams & Wilkins. Muscular System Chapter 11 Part 2.

Contraction of Skeletal Muscles. Physiologic Anatomy of Skeletal Muscle.

© 2012 Pearson Education, Inc. Lecture by Edward J. Zalisko PowerPoint Lectures for Campbell Biology: Concepts & Connections, Seventh Edition Reece, Taylor,

Muscular system SKELETAL MUSCLE Skeletal muscle is made up of hundreds of muscle fibers –Fibers consists of threadlike myofibrils –Myofibrils composed.

Sliding Filament Theory

Warm-Up 4/8/15 1.What is an autoimmune disorder? 2.What how are LEMS and MG similar? 3.How are LEMS and MG different? Test - Tuesday.

09_10 Sliding filament theory Slide number: 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Tropomyosin.

Myofibrils are surrounded by calcium- containing sarcoplasmic reticulum.

Myosin Myosin is a protein molecule found in the thick filaments. Myosin is a protein molecule found in the thick filaments.

Contraction of Skeletal Muscle

OBJECTIVES At the end of this lecture the student should be able to: Define different types of muscles Enumerate cellular organization of human skeletal.

7.2 Microscopic Anatomy and Contraction of Skeletal Muscle

 Name the following movements: ◦ Increasing angle of joint (ex. Straightening arm) ◦ Moving around longitudinal axis: ◦ Moving a limb away from midline.

MUSCLE CONTRACTION. Microscopic Anatomy of Skeletal Muscle Sarcomere Contractile unit of a muscle fiber Figure 6.3b.

Muscle Cells & Muscle Fiber Contractions

Muscles & Skeleton Locomotion Chapter 50. Muscle structure  Muscle fibers  Single cell with many nuclei  Each fiber has a bundle of myofibrils  Each.

Cardiac Muscle Involuntary –heart only Contracts & relaxes continuously throughout life –Contracts without nervous stimulation! –A piece of cardiac muscle.

Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.

Skeletal Muscle Tissue Contraction Chapter 10 Anatomy and Physiology Mr. Knowles Liberty Senior High School.

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Fundamentals of Anatomy & Physiology SIXTH EDITION Frederic H. Martini PowerPoint.

IN CLASS NOTES = STEPS OF A MUSCLE CONTRACTION. STEP 1 Calcium ions present Ca+ binds to troponin which makes tropomyosin move out of way for myosin head.

Question 1 Explain the primary differences between smooth, skeletal, and cardiac muscle tissue Skeletal muscle fibers are cylindrical, multinucleate cells,

Pathophysiology and Management of Hypercyanotic or TET spells Leanne Meakins RN, MN, NP Congenital Cardiac Symposium 25 October 2013.

Interaction of thick & thin filaments __________________ –_____________________________________ _____________________________________ –_____________________________________.

Sliding Filament.

Synapse – The site of connection between a neuron and a cell. Neurotransmitter – A chemical released at the neuron’s synapse that communicates with the.

Muscles & Motor Locomotion Why Do We Need All That ATP?

Chapter 9 Muscles and Muscle Tissue

Three types of muscle Skeletal – attached to bone

The Sliding Filament Theory

Muscular System The 3 Types of Muscles SKELETAL MUSCLE STRUCTURE.

Lecture #21 Date ____ n Chapter 49 ~ Sensory and Motor Mechanisms.

Muscle Contraction. 1.Acetylcholine (Ach) is released from the axon terminal (nerve) into the synaptic cleft and binds to Ach receptors in the sarcolemma.

Muscle voluntary, striated involuntary, striated auto-rhythmic involuntary, non-striated evolved first multi-nucleated digestive system arteries, veins.

Muscle contraction Public domain image. Muscle has two purposes Generate motion Generate force.

MUSCLES LECTURE 14 CHAPTER 12 MECHANISMS OF CONTRACTION.

Muscle Types and Their Characteristics. Skeletal Muscle Anatomy.

MACRO AND MICRO STRUCTURE OF MUSCLE Module 1: Anatomy and Physiology.

Summary of the gross and microscopic changes in cardiac hypertrophy

Muscle Fiber Contraction

Muscle contraction.

Direct and indirect action of free electrons created by ionizing radiation. (Reproduced, with permission, from Hall EJ, Giaccia AJ. Radiobiology for the.

The Ca2+ fluxes and key structures involved in cardiac excitation-contraction coupling. The arrows denote the direction of Ca2+ fluxes. The thickness of.

A practical approach to differentiating tachyarrhythmias

Excitation–Contraction Coupling

Nerve MUSCLE PHYSIOLOGY

Skeletal muscle sarcomere

Arrangement of filaments in striated muscle. (A) Extended

A practical approach to differentiating tachyarrhythmias

Schematic diagram showing arrangement of thick and thin filaments within the sarcomere. Thick filaments contain myosin, myosin-binding protein C, and titin.

Critical pulmonary stenosis

Prayer Homework Attendance.

Skeletal Muscle Microscopic Anatomy

Muscles 19/11/2018 Do it now : (Write in the inner circle)

Muscle Contraction.

SURVEY OF BIOCHEMISTRY Protein Function

The Genetic Basis for Cardiomyopathy

Skeletal Muscle Microscopic Anatomy

Muscle and Muscle Contraction

Between Disease-Causing and an Innocent Bystander: The Role of Titin as a Modifier in Hypertrophic Cardiomyopathy Brenda Gerull, MD Canadian Journal.

Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy

Regulation of Contraction by the Thick Filaments in Skeletal Muscle

Functional organization and properties of skeletal muscles

Presentation transcript:

Schematic diagram showing arrangement of thick and thin filaments within the sarcomere. Thick filaments contain myosin, myosin-binding protein C, and titin. The tails of the myosin heavy chains are woven together to form the thick filament. The globular head projects outward to form crossbridges. The thin filaments include actin (which forms the backbone of the thin filament), the troponins, and tropomyosin. Tropomyosin binds to troponin T at multiple sites along the major groove of the actin filament and inhibits actin-myosin interaction. Troponin T binds the troponin complex to tropomyosin, troponin I inhibits interactions between actin and myosin, and troponin C binds calcium. The sarcomere, which lies between two Z-discs, is anchored by interactions between titin and actin with Z-disc proteins including LIM domain-binding protein 3 (cipher/ZASP), α-actinin, cardiac LIM domain protein (MLP) and telethonin. Adapted from Mahony L. Development of myocardial structure and function. In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, eds. Moss and Adams’ Heart Disease in Infants, Children and Adolescents. 7th ed. Philadelphia, PA. Lippincott Williams & Wilkins; 2008:577. Source: Chapter 2. Regulation of Myocytecontraction and Relaxation, Neonatal Cardiology, 2e Citation: Artman M, Mahony L, Teitel DF. Neonatal Cardiology, 2e; 2011 Available at: http://accesspediatrics.mhmedical.com/DownloadImage.aspx?image=/data/books/artm2/artm2_c002f002.png&sec=40834153&BookID=523&ChapterSecID=40834008&imagename= Accessed: December 26, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved