VSS Refractive Procedure Off-line Programming Module

2Company Confidential © 2010 Abbott Medical Optics Inc. *As compared to AMO Conventional treatment. VSS Refractive Procedure A Better Manifest Refraction-based Solution * The VSS Refractive procedure is a manifest refraction-based LASIK treatment for the STAR S4 IR Excimer Laser System providing a better treatment option for patients who are not eligible for a CustomVue procedure. Better Match to Target Ablation Shape Adjustable Treatment Zones Thermally Optimized IL2715 OUS Version

3Company Confidential © 2010 Abbott Medical Optics Inc. Better Match to Target Ablation Shape Variable Spot Size Scanning (VSS) technology ensures accurate match between the target and ablation shapes Enhanced cosine effect compensation Cosine Effect Compensation IL2715 OUS Version

4Company Confidential © 2010 Abbott Medical Optics Inc. VSS Refractive Treatment Zones Recommended Treatment Dimensions: 1.Myopia: Minimum Optical Zone 6.0 mm Ablation Zone 8.0 mm 2. Hyperopia/Mixed Astigmatism: Minimum Optical Zone 6.0 mm Ablation Zone 9.0 mm Optical and Ablation zones are the same as Advanced CustomVue IL2715 OUS Version Important: All indications may not be available. Treatment indications are subject to availability and are defined in treatment keycards.

VSS Refractive Treatment Zones VSS Refractive Treatment Zones are based on the Minimum Optical Zone. The Maximum Optical Zone is calculated based on the relationship between sphere and cylinder. The larger the amount of cylinder, the larger the Maximum Optical Zone. 5Company Confidential © 2010 Abbott Medical Optics Inc IL2715 OUS Version

6Company Confidential © 2010 Abbott Medical Optics Inc. Adjustable Treatment Zones The VSS Refractive software allows the Minimum Optical Zone and the Ablation Zone to be adjusted: Range of Minimum Optical Zone 3.5 to 8.5 mm Range of Ablation Zone 4.5 to 9.5 mm The Transition Zone (Ablation Zone - Minimum Optical Zone) must be between 1 mm to 4.5 mm. Optical and Ablation zones are the same as Advanced CustomVue IL2715 OUS Version

7Company Confidential © 2010 Abbott Medical Optics Inc. Thermally Optimized The Combination of VSS and VRR technology: –Provides for both thermal balancing and optimal ablation time Variable Repetition Rate (VRR) technology minimizes thermal impact on the cornea. Variable Spot Size Scanning (VSS) technology ensures an accurate match between the target and ablation shapes IL2715 OUS Version

8Company Confidential © 2010 Abbott Medical Optics Inc. VSS (10 Hz) Max = °C VSS + VRR Max = °C Thermally Optimized The addition of VRR technology reduces the peak temperature. Degree Change (°C) Technology simulations. Not actual procedures IL2715 OUS Version

9Company Confidential © 2010 Abbott Medical Optics Inc. VSS Refractive Procedure – A Better Manifest Refractive-based Treatment Option Product Attribute:Advanced CustomVue VSS Refractive Conventional Variable Spot Scanning Variable Repetition RateNo Improved AlgorithmsNo Adjustable Treatment ZonesNo Enhanced Cosine CompensationNo HOA CorrectionNo Iris RegistrationNo Wavefront Guided TreatmentNo IL2715 OUS Version