Stem cells in the embryonic kidney

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Presentation transcript:

Stem cells in the embryonic kidney R. Nishinakamura Kidney International Volume 73, Issue 8, Pages 913-917 (April 2008) DOI: 10.1038/sj.ki.5002784 Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 1 Metanephric mesenchymal progenitors. (a) In vitro colony formation from the metanephric mesenchyme on feeder cells expressing Wnt4. (b) Only Sall1-GFPhigh cells (upper panels) differentiated into kidney structures in organ culture, whereas Sall1-GFPlow cells (lower) disappeared. (c) Hematoxylin–eosin staining of sections of Sall1-GFPhigh aggregates at day 10. Tubule- (t) and glomerulus-like structures (g) are seen. Bars: (a) 50, (b) 500, (c) 25 μm. Kidney International 2008 73, 913-917DOI: (10.1038/sj.ki.5002784) Copyright © 2008 International Society of Nephrology Terms and Conditions

Figure 2 Kidney development in view of stem cell biology. See the text for details. MET, mesenchymal-to-epithelial transition. Kidney International 2008 73, 913-917DOI: (10.1038/sj.ki.5002784) Copyright © 2008 International Society of Nephrology Terms and Conditions