Mannitol, furosemide, and dopamine infusion in postoperative renal failure complicating cardiac surgery Srikrishna Sirivella, MD, Isaac Gielchinsky,

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Presentation transcript:

Mannitol, furosemide, and dopamine infusion in postoperative renal failure complicating cardiac surgery Srikrishna Sirivella, MD, Isaac Gielchinsky, MD, Victor Parsonnet, MD The Annals of Thoracic Surgery Volume 69, Issue 2, Pages 501-506 (February 2000) DOI: 10.1016/S0003-4975(99)01298-9

Fig 1 Outcome in acute postoperative renal failure in 100 patients: Group A (n = 30) were given intermittent administration of diuretics. Subgroup B1 (n = 30) and subgroup B2 (n = 30) were given infusion of mannitol, furosemide, and dopamine 3.5 hours (mean) and 7.5 hours (mean), respectively, after the onset of renal failure. p Values represent group A versus B1 and group A versus B2 both for normal renal function and renal dysfunction. (∗) High output renal failure occurred in subgroup B2 despite diuresis. Renal function returned to preoperative baseline after first postoperative week in subgroup B1 and third postoperative week in subgroup B2. (B1 versus B2 for preop normal renal function: p = NS. B1 versus B2 for preop renal dysfunction: p = 0.024 by Fisher’s exact test.) The Annals of Thoracic Surgery 2000 69, 501-506DOI: (10.1016/S0003-4975(99)01298-9)

Fig 2 Relationship between dose of continuous infusion of solution of mannitol and furosemide with renal doses of dopamine and hourly urine volumes in 56 patients. The Annals of Thoracic Surgery 2000 69, 501-506DOI: (10.1016/S0003-4975(99)01298-9)