Volume 23, Issue 3, Pages (June 2016)

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Volume 23, Issue 3, Pages 426-435 (June 2016) Autologous chondrocyte implantation (ACI) for cartilage defects of the knee: A guideline by the working group “Clinical Tissue Regeneration” of the German Society of Orthopaedics and Trauma (DGOU) P. Niemeyer, D. Albrecht, S. Andereya, P. Angele, A. Ateschrang, M. Aurich, M. Baumann, U. Bosch, C. Erggelet, S. Fickert, H. Gebhard, K. Gelse, D. Günther, A. Hoburg, P. Kasten, T. Kolombe, H. Madry, S. Marlovits, N.M. Meenen, P.E. Müller, U. Nöth, J.P. Petersen, M. Pietschmann, W. Richter, B. Rolauffs, K. Rhunau, B. Schewe, A. Steinert, M.R. Steinwachs, G.H. Welsch, W. Zinser, J. Fritz The Knee Volume 23, Issue 3, Pages 426-435 (June 2016) DOI: 10.1016/j.knee.2016.02.001 Copyright © 2016 Elsevier B.V. Terms and Conditions

Figure 1 Isolated cartilage defect grades III and IV by ICRS classification, with intact corresponding joint surfaces and intact surrounding cartilage, are a suitable indication for ACI. The Knee 2016 23, 426-435DOI: (10.1016/j.knee.2016.02.001) Copyright © 2016 Elsevier B.V. Terms and Conditions

Figure 2 Arthroscopic findings 24months after ACI in the area of the medial femoral condyle with evidence of well-integrated regenerated cartilage. The Knee 2016 23, 426-435DOI: (10.1016/j.knee.2016.02.001) Copyright © 2016 Elsevier B.V. Terms and Conditions

Figure 3 Assistance in making the right choice on the appropriate procedure for biological reconstruction of isolated cartilage defects of the knee depending on various factors (BMS: Bone Marrow Stimulation, e.g. microfracture; ACI, autologous chondrocyte implantation; OCT, osteochondral transplantation). The Knee 2016 23, 426-435DOI: (10.1016/j.knee.2016.02.001) Copyright © 2016 Elsevier B.V. Terms and Conditions