Effect of 2-year placebo-controlled immunotherapy on airway symptoms and medication in patients with birch pollen allergy  Monica B. Arvidsson, MD, Olle.

Slides:



Advertisements
Similar presentations
Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,
Advertisements

Clinical trial design, nasal allergen challenge models, and considerations of relevance to pediatrics, nasal polyposis, and different classes of medication 
House dust mite avoidance measures improve peak flow and symptoms in patients with allergy but without asthma: A possible delay in the manifestation of.
Shin-Ichi Nishikawa, MD, PhD 
Kiwi fruit allergy: A new birch pollen–associated food allergy
Efficacy and safety of birch pollen immunotherapy for local allergic rhinitis  Andrzej Bożek, MD, PhD, Krzysztof Kołodziejczyk, MD, PhD, Jerzy Jarząb,
Oral Phenylephrine HCl for Nasal Congestion in Seasonal Allergic Rhinitis: A Randomized, Open-label, Placebo-controlled Study  Eli O. Meltzer, MD, Paul.
Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with.
Kiwi fruit allergy: A new birch pollen–associated food allergy
Randomized controlled trial of a ragweed allergy immunotherapy tablet in North American and European adults  Peter S. Creticos, MD, Jennifer Maloney,
Ulf Darsow, MD, Dieter Vieluf, MD, Johannes Ring, MD, PhD 
Erika Lerch, MD, Ulrich R. Müller, MD 
Rosa Codina, PhD, Richard F. Lockey, MD 
Aspirin-induced urticaria and angioedema, but not bronchoconstriction, associated with cysteinyl leukotriene overproduction in 2 patients with asthma 
The effect of omalizumab on nasal allergic inflammation
Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis  Paul H. Ratner,
Is 9 more than 2 also in allergic airway inflammation?
Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of.
Practice Notes from the AAAI
Badrul A. Chowdhury, MD, PhD 
Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma  B.Lauren Charous, MD, Elkan F. Halpern,
Comparison of the efficacy of budesonide and fluticasone propionate aqueous nasal spray for once daily treatment of perennial allergic rhinitis  James.
As-needed use of fluticasone propionate nasal spray reduces symptoms of seasonal allergic rhinitis  Albert Jen, MD, Fuad Baroody, MD, Marcy de Tineo,
Edwin A. Bronsky, MD, Howard Druce, MD, Steven R. Findlay, MD, Frank C
Comparison of a nasal glucocorticoid, antileukotriene, and a combination of antileukotriene and antihistamine in the treatment of seasonal allergic rhinitis 
Polymorphism in the gene regulatory region of MCP-1 is associated with asthma susceptibility and severity  Csaba Szalai, PhD, Gergely T. Kozma, BSc, Adrienne.
Allergy to eggs from duck and goose without sensitization to hen egg proteins  Belén Añíbarro, MD, F.Javier Seoane, MD, Concepción Vila, MD, Manuel Lombardero,
Elephantiasis nostras: A case report
Conjunctivitis medicamentosa
Side effects of inhaled corticosteroids
Practice Notes from the AAAAI
Effect of intranasal azelastine and beclomethasone dipropionate on nasal symptoms, nasal cytology, and bronchial responsiveness to methacholine in allergic.
Reply Journal of Allergy and Clinical Immunology
Paul M. O’Byrne, MB, FRCPI, FRCP(C)a, Soren Pedersen, MD, PhDb 
Phillip Lieberman, MD, Michael Tankersley, MD 
Robert A. Wood, MD, Wanda Phipatanakul, MD, Robert G
Legends in allergy: Philip S. Norman and Lawrence M
A review of the current guidelines for allergic rhinitis and asthma
Early decreases in blood eosinophil levels with reslizumab
News & Notes Journal of Allergy and Clinical Immunology
Allergens in school dust: II
Direct exposure of carpets to sunlight can kill all mites
Inflammatory cells, cytokine and chemokine expression in asthma immunocytochemistry and in situ hybridization  Qutayba Hamid, MD, PhD, Editor  Journal.
Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma  Oliver.
Allergen-specific immunotherapy with recombinant grass pollen allergens  Marek Jutel, MD, Lothar Jaeger, MD, Roland Suck, PhD, Hanns Meyer, Dipl Math,
Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma  Mamert Milewski, MD, Lucyna Mastalerz, MD, Ewa Niżankowska, MD, Andrzej.
Patterns of pollen cross-allergenicity
Molecular virology and immunology of HIV infection
Sublingual immunotherapy with once-daily grass allergen tablets: A randomized controlled trial in seasonal allergic rhinoconjunctivitis  Stephen R. Durham,
News & Notes Journal of Allergy and Clinical Immunology
Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic.
Association of humoral immunodeficiency, cleidocranial dysplasia, and von Willebrand’s disease in a family cluster  Pramod S. Kelkar, MD, Rosa M. Ten,
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Emma Broadfield, MRCP, Tricia M
Sublingual grass allergen tablet immunotherapy provides sustained clinical benefit with progressive immunologic changes over 2 years  Ronald Dahl, MD,
Long-term clinical efficacy in grass pollen–induced rhinoconjunctivitis after treatment with SQ-standardized grass allergy immunotherapy tablet  Stephen.
Piotr Kuna, MD, Jadwiga Kaczmarek, MD, Maciej Kupczyk, MD 
Seasonal intestinal inflammation in patients with birch pollen allergy
Practice Notes from the AAAI
Recombinant humanized mAb-E25, an anti-IgE mAb, in birch pollen–induced seasonal allergic rhinitis  Ellinor Ädelroth, MD, PhDa, Sabina Rak, MD, PhDb,
Determinants of systemic manifestations of food allergy
Footnotes1 Journal of Allergy and Clinical Immunology
Evelyn Farinas, RPh, MGA, Peter Honig, MD 
Fiftieth Annual Meeting of the American Academy of Allergy and Immunology: Anaheim, California, March 1994  Lawrence M. Lichtenstein, MD, PhD  Journal.
News & Notes Journal of Allergy and Clinical Immunology
Antihistamine premedication in specific cluster immunotherapy: A double-blind, placebo- controlled study  Lone Nielsen, MD, Claus R. Johnsen, MD, Holger.
Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule 
News Beyond Our Pages Journal of Allergy and Clinical Immunology
Natural history of cow’s milk allergy
A randomized controlled study evaluating medical treatment versus surgical treatment in addition to medical treatment of nasal polyposis  Ebba Hedén Blomqvist,
Presentation transcript:

Effect of 2-year placebo-controlled immunotherapy on airway symptoms and medication in patients with birch pollen allergy  Monica B. Arvidsson, MD, Olle Löwhagen, MD, PhD, Sabina Rak, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 109, Issue 5, Pages 777-783 (May 2002) DOI: 10.1067/mai.2002.123868 Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 1 Mean daily symptom score values in active and placebo groups, each expressed as AUC in relation to the pollen curve during the 1997 season. The differences in AUC between groups were significant (P = .05, counted for the whole season). Journal of Allergy and Clinical Immunology 2002 109, 777-783DOI: (10.1067/mai.2002.123868) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 2 Mean daily symptom score values in active and placebo groups, each expressed as AUC in relation to the pollen curve during the 1998 season. The differences in AUC between groups were significant (P = .005, counted for the whole season). Peak value for the pollen season was 5300 pollen grains/m3, which is not depicted in the figure. Journal of Allergy and Clinical Immunology 2002 109, 777-783DOI: (10.1067/mai.2002.123868) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 3 Mean daily medication score values in active and placebo groups, each expressed as AUC in relation to the pollen curve during the 1997 pollen season. The differences in AUC between groups were significant (P = .004, counted for the whole season). Journal of Allergy and Clinical Immunology 2002 109, 777-783DOI: (10.1067/mai.2002.123868) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 4 Mean daily medication score values in active and placebo groups, each expressed as AUC in relation to the pollen curve during the 1998 pollen season. The differences in AUC between groups were significant (P = .004, counted for the whole season). Peak value for the pollen season was 5300 pollen grains/m3, which is not depicted in the figure. Journal of Allergy and Clinical Immunology 2002 109, 777-783DOI: (10.1067/mai.2002.123868) Copyright © 2002 Mosby, Inc. Terms and Conditions