From: Leber’s Hereditary Optic Neuropathy with Childhood Onset Invest. Ophthalmol. Vis. Sci.. 2006;47(12):5303-5309. doi:10.1167/iovs.06-0520 Figure Legend: RNFL thickness in each quadrant of slowly progressive, acute, and subclinical Leber’s hereditary optic neuropathy (LHON), compared to that in the control group. Compared with the control group, the eyes with acute LHON showed a significantly thinner RNFL in all quadrants. Patients with slowly progressive LHON presented a significant reduction of the temporal quadrant and a not statistically significant reduction of the inferior quadrant. Eyes with a subclinical course showed a reduction (although not statistically significant) of the temporal quadrant and, to a lesser extent, of the inferior quadrant. Date of download: 11/2/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.