Copyright © 2010 American Medical Association. All rights reserved. From: Very Early Neurologic Improvement After Intravenous Thrombolysis Arch Neurol. 2010;67(11):1323-1328. doi:10.1001/archneurol.2010.265 Figure Legend: Comparison of outcome (modified Rankin scale [mRS] score) at 3 months in patients with very early neurologic improvement (VENI) and without VENI. The figure shows the outcome at 3 months according to the presence of greater degrees of neurologic improvement at 1 hour after receiving intravenous recombinant tissue plasminogen activator. Death at 3 months is represented as an mRS score of 6. VENI was defined as a National Institute of Health Stroke Scale score equal to 0 at the 1-hour mark or an improvement of 5 or more points compared with baseline. Date of download: 11/1/2017 Copyright © 2010 American Medical Association. All rights reserved.

Copyright © 2010 American Medical Association. All rights reserved. From: Very Early Neurologic Improvement After Intravenous Thrombolysis Arch Neurol. 2010;67(11):1323-1328. doi:10.1001/archneurol.2010.265 Figure Legend: Receiver operating characteristic curve of the final model for the prediction of favorable outcome at 3 months. The area under the curve of 0.67 indicates an adequate calibration. Date of download: 11/1/2017 Copyright © 2010 American Medical Association. All rights reserved.

Copyright © 2010 American Medical Association. All rights reserved. From: Very Early Neurologic Improvement After Intravenous Thrombolysis Arch Neurol. 2010;67(11):1323-1328. doi:10.1001/archneurol.2010.265 Figure Legend: Favorable outcomes (modified Rankin scale [mRS] scores of ≤1) at 3 months in patients with and without very early neurologic improvement (VENI), stratified by National Institute of Health Stroke Scale (NIHSS) baseline subgroups. On the NIHSS, scores of 0 through 10 indicate mild to moderate stroke (n = 22 patients); scores of 11 through 20, severe stroke (n = 86 patients); and scores of greater than 20, very severe stroke (n = 12 patients). Date of download: 11/1/2017 Copyright © 2010 American Medical Association. All rights reserved.

Copyright © 2010 American Medical Association. All rights reserved. From: Very Early Neurologic Improvement After Intravenous Thrombolysis Arch Neurol. 2010;67(11):1323-1328. doi:10.1001/archneurol.2010.265 Figure Legend: Favorable outcomes (modified Rankin scale [mRS] scores of ≤1) at 3 months according to major neurologic improvement at 24 hours in patients with and without very early neurologic improvement (VENI). Major neurologic improvement (MNI) at 24 hours was defined by an 8-point or greater improvement in National Institute of Health Stroke Scale (NIHSS) score or an NIHSS score of 0 or 1 at 24 hours. Date of download: 11/1/2017 Copyright © 2010 American Medical Association. All rights reserved.