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Volume 195, Issue 5, Pages 1409-1414 (May 2016) Metastatic Prostate Cancer in Men Initially Treated with Active Surveillance Toshihiro Yamamoto, Bindu Musunuru, Danny Vesprini, Liying Zhang, Gabriella Ghanem, Andrew Loblaw, Laurence Klotz The Journal of Urology Volume 195, Issue 5, Pages 1409-1414 (May 2016) DOI: 10.1016/j.juro.2015.11.075 Copyright © 2016 American Urological Association Education and Research, Inc. Terms and Conditions

Figure 1 Kaplan-Meier overall metastasis-free survival (MFS) with 95% CI in all patients. The Journal of Urology 2016 195, 1409-1414DOI: (10.1016/j.juro.2015.11.075) Copyright © 2016 American Urological Association Education and Research, Inc. Terms and Conditions

Figure 2 Kaplan-Meier metastasis-free survival in patients with PSA doubling time 3 years or less, or more than 3 years. The Journal of Urology 2016 195, 1409-1414DOI: (10.1016/j.juro.2015.11.075) Copyright © 2016 American Urological Association Education and Research, Inc. Terms and Conditions

Figure 3 Kaplan-Meier metastasis-free survival in patients in low and intermediate risk groups. The Journal of Urology 2016 195, 1409-1414DOI: (10.1016/j.juro.2015.11.075) Copyright © 2016 American Urological Association Education and Research, Inc. Terms and Conditions

Figure 4 Kaplan-Meier metastasis-free survival in patients with PSA greater than 10 ng/ml or GS 7. The Journal of Urology 2016 195, 1409-1414DOI: (10.1016/j.juro.2015.11.075) Copyright © 2016 American Urological Association Education and Research, Inc. Terms and Conditions