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Volume 185, Issue 2, Pages (February 2011)

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Presentation on theme: "Volume 185, Issue 2, Pages (February 2011)"— Presentation transcript:

1 Volume 185, Issue 2, Pages 706-711 (February 2011)
Sarcosine in Prostate Cancer Tissue is Not a Differential Metabolite for Prostate Cancer Aggressiveness and Biochemical Progression  Florian Jentzmik, Carsten Stephan, Michael Lein, Kurt Miller, Beate Kamlage, Bianca Bethan, Glen Kristiansen, Klaus Jung  The Journal of Urology  Volume 185, Issue 2, Pages (February 2011) DOI: /j.juro Copyright © 2011 American Urological Association Education and Research, Inc. Terms and Conditions

2 Figure 1 Sarcosine in 92 matched malignant and nonmalignant prostatectomy samples (A), and in malignant samples categorized by pathological stage pT2 vs pT3 (B), and by prostatectomy based Gleason score less than 7 vs 7 or greater (C). Differences were tested by the Wilcoxon matched pairs (A) and Mann-Whitney U (B and C) tests. The Journal of Urology  , DOI: ( /j.juro ) Copyright © 2011 American Urological Association Education and Research, Inc. Terms and Conditions

3 Figure 2 Kaplan-Meier curves were calculated for biochemical recurrence-free time after surgery by pathological tumor stage pT2 vs pT3 (A), tumor grade with Gleason score less than 7, 7 and greater than 7 (B), and sarcosine less vs greater than median (C). Differences were tested by log rank test. Blue curve indicates pT2a to pT2b (A), Gleason score less than 7 (B) and less than median (C). Green curve indicates pT3a to pT3b (A), Gleason score 7 (B) and median (C). Red curve indicates Gleason score greater than 7 (C). Tick marks indicate censored. The Journal of Urology  , DOI: ( /j.juro ) Copyright © 2011 American Urological Association Education and Research, Inc. Terms and Conditions


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