Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner

Positron Emission Tomography Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner PET? Positron Emission Tomography

(The most widely used radiopharmaceutical is fluorodeoxyglucose) Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner A radioisotope that undergoes β+ (or positron, e+) decay is combined with glucose and injected into the bloodstream. (The most widely used radiopharmaceutical is fluorodeoxyglucose) The glucose compound is absorbed into the body tissues and used as normal glucose in respiration

It is inhaled by the patient to enable lung function to be studied Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner Alternatively, a positron emitting isotope of oxygen (O-15) can be used. It is inhaled by the patient to enable lung function to be studied

Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner Detection After a decay has occurred and a positron is released it will typically travel less than 1mm before annihilating with an electron. This produces two gamma photons with energy of 511keV travelling in opposite directions

Be able to describe the principles of PET scanning Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner

Be able to describe the principles of PET scanning Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner                                                                                                                           

The patient is surrounded by a ring of gamma ray detectors Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner The patient is surrounded by a ring of gamma ray detectors - scintillation detectors and photomultiplier tubes A computer analyses the time differences in the detection of the two gamma rays Processing the input to the array of detectors allows an image of the organ to be produced. Colour is used to signify the amount of radiation being detected at a certain point.

Answer Q3 Page 208 Be able to describe the principles of PET scanning Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner Answer Q3 Page 208

What does PET allow us to study? Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner What does PET allow us to study? We can compare the rates of respiration of the parts of organs

More gamma photons will be detected from regions of cancerous tissue Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner Cancer Cancer cells have a greater division and growth rate, requiring more energy Clusters of cancer cells will take in more of the radiolabelled glucose More gamma photons will be detected from regions of cancerous tissue

The heart shows up clearly and the kidneys can be seen The heart shows up clearly and the kidneys can be seen. The brightest area shows that there is cancer in a rib. heart kidney tumour

Allows the study of brain trauma, epilepsy, Alzheimers Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner The Brain Active parts of the brain will require more energy and hence will have a higher respiration rate Allows the study of brain trauma, epilepsy, Alzheimers

Be able to describe the principles of PET scanning Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner

Be able to describe the principles of PET scanning Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner

Be able to describe the principles of PET scanning Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner

Combining PET and CT scanning in one machine Learning Objectives By the end of this lesson you should… Be able to describe the principles of PET scanning Be able to describe the structure of a PET scanner Development of imaging techniques… Combining PET and CT scanning in one machine CT scan identifies bones and organs and superimposing the PET scan image over this allows easier location of tumour sites