Samira M. Azarin, Sean P. Palecek Cell Stem Cell

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Presentation transcript:

Matrix Revolutions: A Trinity of Defined Substrates for Long-Term Expansion of Human ESCs Samira M. Azarin, Sean P. Palecek Cell Stem Cell Volume 7, Issue 1, Pages 7-8 (July 2010) DOI: 10.1016/j.stem.2010.06.008 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 Schematic Depicting Three Defined Substrates that Enable Expansion of Human Embryonic Stem Cells (A) Recombinant human laminin-511 adsorbed to tissue culture polystyrene, (B) extracellular matrix protein-derived peptides covalently linked to an acrylate coating, and (C) the synthetic methacrylate-based polymer, poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl)ammonium hydroxide] (PMEDSAH), were shown to facilitate adhesion and self-renewal of human embryonic stem cell lines. Cell Stem Cell 2010 7, 7-8DOI: (10.1016/j.stem.2010.06.008) Copyright © 2010 Elsevier Inc. Terms and Conditions