Genetic Diseases & Disorders Mrs. Anna Ward James Martin MS

Do NOW!!!! Page 24 How many females are represented? How many males? How many people have the disease? How many are males with the disease? How many are females with the disease? How many generations are represented? How many marriages do you see? How many children did the couple in the first generation have?

Announcements Notebook Check next Friday Last one of the quarter

Agenda for today: Quiz 6: Pedigrees Mutations & Genetic Disease What is a mutation? Is it a good thing or a bad thing? Benefits to Mutations Disorders & Diseases associated with Genetic Mutations Jigsaw Diseases: Huntington’s Disease Down’s Syndrome Klinefelter’s Syndrome Albinism Hemophilia

Mutations A mutation is any change in the DNA. The change can be positive, negative or have no effect at all. The mutation may have a small or large effect. MUTATIONS are not what we think of from Sci-Fi/Horror Movies! http://www.brainpop.com/science/cellularlifeandgenetics/geneticmuta tions/

Effect of mutations in Humans

Let’s look at some diseases (jigsaw) Sickle Cell (We covered this Tuesday) Klinefelter’s Huntington’s Down’s Syndrome Hemophilia Albinism Cancer

For your disorder… Answer as many questions on your provided sheet. Make sure ALL of the group members’ names are on the sheet. Take this information and create a poster using the white paper. USE CREATIVITY!!!!!1 ON MONDAY….you will have a few moments to complete your disease posters if needed. Your group will present the information about your disease. I will find a short video to help enhance your presentation.