Multicystic Dysplastic Kidney Disease Presenting With a Single Large Cyst in a Fetus– Anatomical Basis and Radiological Aspects Fong-Fong Lim, Teng-Fu.

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Multicystic Dysplastic Kidney Disease Presenting With a Single Large Cyst in a Fetus– Anatomical Basis and Radiological Aspects Fong-Fong Lim, Teng-Fu Tsao, Hung-Ming Chang, Ji-Nan Sheu Pediatrics & Neonatology Volume 52, Issue 4, Pages 227-231 (August 2011) DOI: 10.1016/j.pedneo.2011.05.009 Copyright © 2011 Terms and Conditions

Figure 1 Prenatal ultrasound examination of the fetus. (A) At the 21st week of gestation a single large fluid-filled mass situated in the left renal fossa and a mild pelvic dilatation in the right kidney were seen. (B) At the 27th week of gestation, similar findings of an enlarged left renal pelvis and a mild hydronephrosis in the contralateral kidney were revealed. (C) Postnatal ultrasound examination revealed a single predominant large cystic mass occupying the left renal space, which was surrounded by a few small noncommunicating cysts in the lower pole of the mass. Pediatrics & Neonatology 2011 52, 227-231DOI: (10.1016/j.pedneo.2011.05.009) Copyright © 2011 Terms and Conditions

Figure 2 Fetal abdominal magnetic resonance imaging performed at the 21st week of gestation. (A) T2-weighted coronal image showed a single predominant cystic lesion in the left side of the abdomen (long arrow). The image also revealed a nondistended bladder (short arrow). (B) T2-weighted axial image showed a large cyst occupying the left renal fossa (long arrow). A slightly dilated pelvis of the right kidney was also visible (arrowheads). A normal gallbladder was evident (short arrow). Pediatrics & Neonatology 2011 52, 227-231DOI: (10.1016/j.pedneo.2011.05.009) Copyright © 2011 Terms and Conditions

Figure 3 Pathological findings of the resected mass. (A) The gross specimen showed the excised dysplastic kidney with a single predominant large cystic mass surrounded by a few small cysts in the lower pole. (B) Histopathological appearance of the MCDK was composed of multiple cystic spaces of varying sizes lined by a cuboidal or flattened epithelium. The renal parenchyma showed primitive glomeruli, tubules, and dysplastic mesenchyma including cartilage and fibromuscular tissue (Hematoxylin and eosin stain, 40×). Pediatrics & Neonatology 2011 52, 227-231DOI: (10.1016/j.pedneo.2011.05.009) Copyright © 2011 Terms and Conditions