Why are most clinical research findings not spectacular?

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Presentation transcript:

Why are most clinical research findings not spectacular? Morten Hylander Møller, Ass. Professor, MD, PhD, EDIC Dept. of Intensive Care 4131 Copenhagen University Hospital Rigshospitalet Denmark

Summary Bias Effect Savovic et al. Ann. Int. Med. 2012

Summary Research findings Blinding Design Fragility Pre-test probability Financial bias Outcomes Effect size Data fabrication Predefined analyses Random errors Publication bias

Summary Patient-centred care Year

”We need less research, better research, and research done for the right reasons” Douglas Altman, 1948-